SCHEMBL13085352

SCHEMBL13085352

Cc1cc(Cl)cc(C(=O)NC(C)CF)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DGAT2 Q96PD7 1/20 0.30
NTRK1 P04629 7/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13084965 0.95 ALDH1A1 (0.32) DHODHALDH1A1SMN1; SMN2DGAT2
SCHEMBL685545 0.94 DHODH (0.33) DHODHALDH1A1SMN1; SMN2NTRK1
SCHEMBL13084941 0.94 DHODH (0.31) DHODHDGAT2
SCHEMBL10089961 0.92 WDR5 (0.34) DHODHALDH1A1SMN1; SMN2DGAT2
SCHEMBL10089860 0.91 PTGER4 (0.35) DGAT2
SCHEMBL10089968 0.91 PTGER4 (0.35) DGAT2
SCHEMBL10089877 0.91 PTGER4 (0.35) DHODHDGAT2
SCHEMBL685542 0.91 DHODH (0.33) DHODHALDH1A1SMN1; SMN2NTRK1
SCHEMBL13084810 0.91 WDR5 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL10090016 0.91 PTGER4 (0.35) DHODHDGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 DHODH 2604/4885ALDH1A1 3779/4885SMN1; SMN2 3923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.