SCHEMBL13096211

SCHEMBL13096211

COC(c1ccccc1)(c1ccccc1)[C@@H]1CCCN1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CHRNB4 P30926 3/20 0.36
CHRNA3 P32297 3/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CHRM3 P20309 4/20 0.35
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2B6 P20813 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12563197 0.80 LMNA (0.43) LMNACHRNB4CHRNA3ATML3MBTL1
SCHEMBL13105272 0.80 CHRNB4 (0.45) LMNACHRNB4CHRNA3ATML3MBTL1
SCHEMBL13067181 0.80 CHRNB4 (0.45) LMNACHRNB4CHRNA3ATML3MBTL1
SCHEMBL19362506 0.80 CHRNB4 (0.45) LMNACHRNB4CHRNA3ATML3MBTL1
SCHEMBL13676359 0.79 LMNA (0.56) LMNAATML3MBTL1CHRM3KDM4E
SCHEMBL13676375 0.79 LMNA (0.56) LMNAATML3MBTL1CHRM3KDM4E
SCHEMBL28385294 0.77 LMNA (0.38) LMNAATML3MBTL1CHRM3
SCHEMBL24621749 0.71 NUDT1 (0.35)
SCHEMBL27163807 0.68 PLA2G1B (0.45) LMNACHRNB4CHRNA3L3MBTL1CYP3A4
SCHEMBL27163810 0.68 PLA2G1B (0.45) LMNACHRNB4CHRNA3L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US disclosed
US-20100256329-A1 STEREOSELECTIVE ALTERNATING COPOLYMERIZATION OF EPOXIDE WITH CARBON DIOXIDE THE UNIVERSITY OF TOKYO (JP) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 LMNA 3764/4885CHRNB4 2123/4885CHRNA3 2761/4885
US-20100256329-A1 STEREOSELECTIVE ALTERNATING COPOLYMERIZATION OF EPOXIDE WITH CARBON DIOXIDE PCNA, HPD, TET3 LMNA 3481/4885CHRNB4 443/4885CHRNA3 311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.