Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801076 | 0.83 | TNF (0.59) | TNFNOD1NPC1RAB9AKDM4E | |
| SCHEMBL19735284 | 0.83 | APP (0.48) | TNFNOD1NPC1RAB9AKDM4E | |
| SCHEMBL26502567 | 0.83 | KIF11 (0.41) | NPC1RAB9AKDM4EAPPKIF11 | |
| SCHEMBL26500137 | 0.80 | NPBWR1 (0.39) | NPC1RAB9AKDM4EAPPKIF11 | |
| SCHEMBL26500172 | 0.77 | HSD17B1 (0.47) | NPC1RAB9AKDM4EAPPMAPT | |
| SCHEMBL10301434 | 0.76 | HSD17B1 (0.47) | NPC1RAB9AKDM4EAPPMAPT | |
| SCHEMBL17994290 | 0.76 | HSD17B1 (0.52) | TNFNOD1NPC1RAB9AKDM4E | |
| SCHEMBL1622295 | 0.76 | KIF11 (0.47) | TNFNOD1NPC1RAB9AKDM4E | |
| SCHEMBL26500204 | 0.75 | HSD17B1 (0.46) | NPC1RAB9AKDM4EAPPMAPT | |
| SCHEMBL27961851 | 0.74 | APP (0.41) | TNFNOD1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812172-B2 | Charge transport materials; for organic electronic devices such as organic photoreceptors, organic electroluminescence devices, organic transistors, and organic optical memories | FUJI XEROX CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-7812172-B2 | Charge transport materials; for organic electronic devices such as organic photoreceptors, organic electroluminescence devices, organic transistors, and organic optical memories | FUJI XEROX CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137611-A1 | THIAZOLOTHIAZOLE DERIVATIVE | BCAT1, ABAT, BCAT2 | TNF 2822/4885NOD1 1329/4885NPC1 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.