Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311281 | 0.89 | MEN1 (0.44) | BLMTSHRUSP2MEN1KMT2A | |
| SCHEMBL1312472 | 0.87 | PTPRB (0.43) | BLMESR1TSHRUSP2ESR2 | |
| SCHEMBL1311029 | 0.83 | BLM (0.43) | BLMESR1TSHRUSP2ESR2 | |
| SCHEMBL1310603 | 0.82 | MMP8 (0.44) | KMT2ACYP3A4MAPTALDH1A1HTT | |
| SCHEMBL1311213 | 0.81 | ALDH1A1 (0.38) | BLMLMNACYP3A4MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1310637 | 0.81 | ALDH1A1 (0.37) | BLMLMNACYP3A4MAPTALDH1A1 | |
| SCHEMBL1310654 | 0.81 | CYP1A2 (0.43) | MEN1KMT2ACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1311319 | 0.80 | TACR3 (0.43) | BLMTSHRMEN1KMT2ACYP2C9 | |
| Hydrochloric Acid SCHEMBL1311604 | 0.79 | TACR3 (0.42) | BLMTSHRMEN1KMT2ACYP2C9 | |
| SCHEMBL1312278 | 0.76 | PTPRB (0.42) | TSHRUSP2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (SE) | 2011-11-10 | — | — | US | disclosed |
| EP-2310368-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | ADIPOR2, GPR119, ADIPOR1 | BLM 4452/4885ESR1 1456/4885TSHR 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.