Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.51 |
| ▸ | WNT3A | P56704 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21770322 | 0.93 | HPGD (0.55) | ALDH1A1HPGDCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL21770378 | 0.83 | CTNNB1 (0.44) | ALDH1A1HPGDMEN1KMT2ACTNNB1 | |
| SCHEMBL21753357 | 0.81 | CTNNB1 (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL28496847 | 0.78 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8242151 | 0.77 | CTNNB1 (0.52) | ALDH1A1KDM4EMEN1KMT2ACTNNB1 | |
| SCHEMBL24350075 | 0.76 | NPC1 (0.54) | MEN1KMT2ARAB9AGAA | |
| SCHEMBL4085154 | 0.76 | MGLL (0.48) | MEN1KMT2AGAAMAOB | |
| SCHEMBL1760150 | 0.76 | HDAC1 (0.49) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL1929771 | 0.76 | SIGMAR1 (0.52) | MEN1KMT2AGAA | |
| SCHEMBL15162004 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2021-07-15 | — | — | US | disclosed |
| WO-2020039027-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |
| US-7807691-B2 | Substituted N-arylpyrrolidines as selective androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2010-10-05 | — | — | US | disclosed |
| US-7807691-B2 | Substituted N-arylpyrrolidines as selective androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1891038-B1 | SUBSTITUTED N-ARYLPYRROLIDINES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20080176864-A1 | Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators | ELI LILLY AND COMPANY | 2008-07-24 | — | — | US | disclosed |
| US-20080176864-A1 | Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators | ELI LILLY AND COMPANY | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | ALDH1A1 1182/4885KDM4E 2209/4885HPGD 1673/4885 |
| US-20080176864-A1 | Substituted N-Arylpyrrolidines as Selective Androgen Receptor Modulators | AR, FSHR, SHBG | ALDH1A1 1474/4885KDM4E 2955/4885HPGD 429/4885 |
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | PREP, GAA, DNPEP | ALDH1A1 1170/4885KDM4E 1934/4885HPGD 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.