Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311799 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1GAAALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1310404 | 0.78 | ALDH1A1 (0.46) | KMT2AMEN1GAAALDH1A1CYP3A4 | |
| SCHEMBL1310767 | 0.78 | CYP3A4 (0.46) | KMT2AMEN1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1311175 | 0.77 | LAP3 (0.52) | KMT2AMEN1PKMALDH1A1CYP3A4 | |
| SCHEMBL1311161 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1GAAALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1311848 | 0.76 | LAP3 (0.51) | KMT2AMEN1PKMALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1311058 | 0.76 | ALDH1A1 (0.46) | KMT2AMEN1GAAALDH1A1CYP3A4 | |
| SCHEMBL1311414 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1311546 | 0.74 | GPR142 (0.52) | KMT2APKMALDH1A1CYP3A4HTT | |
| SCHEMBL1311477 | 0.74 | GPR142 (0.52) | KMT2APKMALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (SE) | 2011-11-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | ADIPOR2, GPR119, ADIPOR1 | KMT2A 2294/4885MEN1 3508/4885GAA 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.