Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.49 |
| ▸ | TCF4 | P15884 | 7/20 | 0.49 |
| ▸ | CDH1 | P12830 | 2/20 | 0.49 |
| ▸ | APC | P25054 | 2/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cercosporin SCHEMBL29613349 | 0.81 | TCF4 (0.71) | CTNNB1TCF4CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL6305985 | 0.81 | TCF4 (0.71) | CTNNB1TCF4CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL498747 | 0.81 | TCF4 (0.71) | CTNNB1TCF4CDH1APCTCF7L2 | |
| SCHEMBL29929662 | 0.81 | CTNNB1 (0.68) | CTNNB1TCF4CDH1APCTCF7L2 | |
| SCHEMBL29711267 | 0.81 | CTNNB1 (0.68) | CTNNB1TCF4CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL28102616 | 0.80 | TCF4 (0.70) | CTNNB1TCF4CDH1APCTCF7L2 | |
| SCHEMBL3673245 | 0.80 | MGAM (0.40) | CTNNB1TCF4MGAMCTSV | |
| Cercosporin SCHEMBL21175561 | 0.77 | TCF4 (0.65) | CTNNB1TCF4CDH1APCTCF7L2 | |
| SCHEMBL15507806 | 0.76 | CTNNB1 (0.35) | CTNNB1TCF4CDH1APCTCF7L2 | |
| SCHEMBL22930428 | 0.76 | TCF4 (0.64) | CTNNB1TCF4CDH1APCTCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816563-B1 | Method for preparing hypocrellin | Alberta Innovates-Technology Futures (CA) | 2010-10-19 | — | — | US | disclosed |
| US-7816563-B1 | Method for preparing hypocrellin | Alberta Innovates-Technology Futures (CA) | 2010-10-19 | — | — | US | disclosed |