Cercosporin

Cercosporin

SCHEMBL498747

COc1c(C[C@@H](C)O)c2c3c(C[C@@H](C)O)c(OC)c(=O)c4c(O)cc5c(c6c(cc(O)c(c1=O)c62)OCO5)c43

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TCF4 P15884 5/20 0.71
CTNNB1 P35222 5/20 0.71
CDH1 P12830 1/20 0.71
APC P25054 1/20 0.71
TCF7L2 Q9NQB0 1/20 0.71
GAA P10253 2/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 1/20 0.35
HDAC1 Q13547 1/20 0.34
P4HB P07237 3/20 0.33
SMPD1 P17405 1/20 0.33
SMAD3 P84022 3/20 0.33
CDK2 P24941 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cercosporin SCHEMBL29613349 1.00 TCF4 (0.71) TCF4CTNNB1CDH1APCTCF7L2
Cercosporin SCHEMBL6305985 1.00 TCF4 (0.71) TCF4CTNNB1CDH1APCTCF7L2
Cercosporin SCHEMBL15185706 1.00 TCF4 (0.71) TCF4CTNNB1CDH1APCTCF7L2
Cercosporin SCHEMBL28102616 0.99 TCF4 (0.70) TCF4CTNNB1CDH1APCTCF7L2
Cercosporin SCHEMBL21175561 0.94 TCF4 (0.65) TCF4CTNNB1CDH1APCTCF7L2
SCHEMBL22930428 0.94 TCF4 (0.64) TCF4CTNNB1CDH1APCTCF7L2
SCHEMBL29369377 0.83 CTNNB1 (1.00) TCF4CTNNB1CDH1APCTCF7L2
SCHEMBL13121634 0.81 CTNNB1 (0.49) TCF4CTNNB1CDH1APCTCF7L2
SCHEMBL8476647 0.71 TCF4 (0.42) TCF4CTNNB1CDH1APCTCF7L2
SCHEMBL29711267 0.66 CTNNB1 (0.68) TCF4CTNNB1CDH1APCTCF7L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4007582-B1 ANTIBIOTICS IN COMBINATION WITH PHOTODYNAMIC THERAPY FOR USE IN A METHOD OF ENHANCING THE ANTIMICROBIAL ACTION OF SYSTEMICALLY ADMINISTERED ANTIBIOTICS KOITE HEALTH OY (FI) 2026-05-20 EP claimed
US-20260131003-A1 Method and kit for treating skin infections KOITE HEALTH OY (FI) 2026-05-14 US claimed
EP-4255560-B1 KIT FOR TREATMENT OF PATIENTS HAVING DRY MOUTH SYNDROME KOITE HEALTH OY (FI) 2026-04-22 EP claimed
US-12606649-B2 Process for preparation of polyisobutene derivatives BASF SE (DE) 2026-04-21 US claimed
US-12521436-B2 Method and kit for treating skin infections KOITE HEALTH OY (FI) 2026-01-13 US claimed
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-09-25 US claimed
EP-4577516-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP claimed
EP-4577517-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP claimed
CN-119744258-A Process for the preparation of 4-hydroxy-2-methylene-butyraldehyde, 4-hydroxy-2-methyl-but-2-enal and their esters 巴斯夫欧洲公司 2025-04-01 CN claimed
CN-119744259-A Process for the preparation of 4-hydroxy-2-methylene-butyraldehyde, 4-hydroxy-2-methyl-but-2-enal and their esters 巴斯夫欧洲公司 2025-04-01 CN claimed
EP-0934401-A1 FUNGAL GENE ENCODING RESISTANCE TO THE PHYTOTOXIN CERCOSPORIN The United States of America, represented by The Secretary of Agriculture (US) 1999-08-11 EP claimed
WO-1998041082-A9 ISOLATED GENES AND PROTEINS ENCODING RESISTANCE TO PHOTOSENSITIZERS 1999-03-04 WO claimed
WO-1998041612-A1 CERCOSPORIN-DEGRADING BACTERIA NORTH CAROLINA STATE UNIVERSITY (US) 1998-09-24 WO claimed
WO-1998041082-A1 ISOLATED GENES AND PROTEINS ENCODING RESISTANCE TO PHOTOSENSITIZERS NORTH CAROLINA STATE UNIVERSITY (US) 1998-09-24 WO claimed
WO-1998033470-A2 SUBSTITUTED PERYLENEQUINONES FOR USE IN PHOTODYNAMIC THERAPY ALTAREX CORP. (CA) 1998-08-06 WO claimed
WO-1997035001-A1 FUNGAL GENE ENCODING RESISTANCE TO THE PHYTOTOXIN CERCOSPORIN THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1997-09-25 WO claimed
CN-1143070-A Photochemical method for preparation of 13-Cis retinoic acid LAB MAG SPA (IT) 1997-02-19 CN claimed
EP-0742204-A1 Photochemical method for the preparation of 13-cis-retinoic acid LABORATORI MAG S.p.A. (IT) 1996-11-13 EP claimed
US-5262306-A Degradation of cercosporin fungi by culturing microbes in agar and detection and extraction NOVARTIS AG (CH) 1993-11-16 US claimed
WO-1991005061-A1 METHODS FOR IDENTIFYING CERCOSPORIN-DEGRADING MICROORGANISMS AND PRODUCING CERCOSPORIN-RESISTANT PLANT SPECIES THE PLANT CELL RESEARCH INSTITUTE INCORPORATED (US) 1991-04-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF ALDH1A2, ADH4, RBP4 TCF4 1309/4885CTNNB1 1282/4885CDH1 2707/4885
US-12606649-B2 Process for preparation of polyisobutene derivatives TCP1, POLD1, VAPA TCF4 2592/4885CTNNB1 48/4885CDH1 1115/4885
US-20260131003-A1 Method and kit for treating skin infections CUTA, KIT, FLNB TCF4 1537/4885CTNNB1 141/4885CDH1 281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.