Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 5/20 | 0.71 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.71 |
| ▸ | CDH1 | P12830 | 1/20 | 0.71 |
| ▸ | APC | P25054 | 1/20 | 0.71 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 3/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cercosporin SCHEMBL15185706 | 1.00 | TCF4 (0.71) | TCF4CTNNB1CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL29613349 | 1.00 | TCF4 (0.71) | TCF4CTNNB1CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL498747 | 1.00 | TCF4 (0.71) | TCF4CTNNB1CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL28102616 | 0.99 | TCF4 (0.70) | TCF4CTNNB1CDH1APCTCF7L2 | |
| Cercosporin SCHEMBL21175561 | 0.94 | TCF4 (0.65) | TCF4CTNNB1CDH1APCTCF7L2 | |
| SCHEMBL22930428 | 0.94 | TCF4 (0.64) | TCF4CTNNB1CDH1APCTCF7L2 | |
| SCHEMBL29369377 | 0.83 | CTNNB1 (1.00) | TCF4CTNNB1CDH1APCTCF7L2 | |
| SCHEMBL13121634 | 0.81 | CTNNB1 (0.49) | TCF4CTNNB1CDH1APCTCF7L2 | |
| SCHEMBL8476647 | 0.71 | TCF4 (0.42) | TCF4CTNNB1CDH1APCTCF7L2 | |
| SCHEMBL29711267 | 0.66 | CTNNB1 (0.68) | TCF4CTNNB1CDH1APCTCF7L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624949-B1 | Methods for treating diseases related to the wnt pathway | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2020-04-21 | — | — | US | disclosed |
| US-20050175593-A1 | Degradation of Cercosporin by laccase | LARTEY ROBERT T (US) | 2005-08-11 | — | — | US | disclosed |
| US-6872388-B1 | Degradation of cercosporin by laccase | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2005-03-29 | — | — | US | disclosed |
| US-6077995-A | CERCOSPORA NUCLEOTIDE SEQUENCES WHICH CODES A MEMBRANE PUMP PROTEIN; FOR PREVENTION OF PLANT SENSITIVITY TO FUNGAL TOXIN | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2000-06-20 | — | — | US | disclosed |