Hydroquinone

Hydroquinone

SCHEMBL131228

O=P(O)(O)O.Oc1ccc(O)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.61
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
LMNA P02545 3/20 0.61
MAPT P10636 3/20 0.61
CA3 P07451 3/20 0.61
CA14 Q9ULX7 3/20 0.61
ALOX15 P16050 3/20 0.61
CYP3A4 P08684 3/20 0.61
HIF1A Q16665 3/20 0.61
ALDH1A1 P00352 3/20 0.61
HPGD P15428 2/20 0.61
KDM4E B2RXH2 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
TYR P14679 2/20 0.61
CA4 P22748 2/20 0.61
CA5A P35218 2/20 0.61
CA9 Q16790 2/20 0.61
CA5B Q9Y2D0 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL329315 1.00 CA12 (0.61) CA12CA1CA2LMNAMAPT
Hydroquinone SCHEMBL14718054 0.93 ESR1 (0.56) CA12CA1CA2LMNAMAPT
Hydroquinone SCHEMBL21291909 0.87 CA2 (0.65) CA12CA1CA2LMNAMAPT
4-Aminophenol SCHEMBL28849641 0.85 CYP3A4 (0.72) CA12CA1CA2LMNAMAPT
P-Cresol SCHEMBL28453798 0.85 ACHE (0.72) CA12CA1CA2LMNAMAPT
Phosphoric Acid SCHEMBL1641459 0.85 APP (0.45) CA12CA1CA2LMNAMAPT
4-Aminophenol SCHEMBL78547 0.85 CYP3A4 (0.72) CA12CA1CA2LMNAMAPT
P-Cresol SCHEMBL30644866 0.85 ACHE (0.72) CA12CA1CA2LMNAMAPT
Phosphoric Acid SCHEMBL29167223 0.85 CA12 (0.44) CA12CA1CA2LMNAMAPT
P-Cresol SCHEMBL30339010 0.85 ACHE (0.72) CA12CA1CA2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111592826-B Reactive self-adhesive flame-retardant waterproof asphalt coating 厦门稀土材料研究所 2021-07-20 CN claimed
EP-3390489-B1 POLYCONDENSATE BASED WATER-REDUCER CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2020-09-09 EP claimed
CN-111592826-A Reactive self-adhesive flame-retardant waterproof asphalt coating 厦门稀土材料研究所 2020-08-28 CN claimed
US-20190010090-A1 POLYCONDENSATE BASED WATER-REDUCER BASF CONSTRUCTION SOLUTIONS GMBH (DE) 2019-01-10 US claimed
EP-3390489-A1 POLYCONDENSATE BASED WATER-REDUCER Construction Research & Technology GmbH (DE) 2018-10-24 EP claimed
WO-2017103215-A9 POLYCONDENSATE BASED WATER-REDUCER CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2018-09-07 WO claimed
US-10031134-B2 Antibody-nanoparticle conjugates and methods for making and using such conjugates VENTANA MEDICAL SYSTEMS, INC. (US) 2018-07-24 US claimed
CN-106947158-A A kind of Halogen high-impact anti-flaming polypropylene material 绵阳朗迪新材料有限公司 2017-07-14 CN claimed
WO-2017103215-A1 POLYCONDENSATE BASED WATER-REDUCER CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2017-06-22 WO claimed
EP-2564203-B1 ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES VENTANA MED SYST INC (US) 2017-06-07 EP claimed
US-7642064-B2 Binding enzyme-labeled conjugate (antibodies, haptens with phospatases, galactosidases, beta-glucosidases, esterases, and beta-lactamases) to epitope/sequence in presence of redox-inactive reductive species and soluble gold/silver ion; solid phase synthesis; kits VENTANA MEDICAL SYSTEMS, INC. (US) 2010-01-05 US claimed
US-7632652-B2 Binding enzyme-labeled conjugate (antibodies, haptens with phospatases, galactosidases, beta-glucosidases, esterases, and beta-lactamases) to epitope/sequence in presence of redox-inactive reductive species and soluble gold/silver ion; kits VENTANA MEDICAL SYSTEMS, INC. (US) 2009-12-15 US claimed
EP-1636586-B1 ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES VENTANA MED SYST INC (US) 2009-07-22 EP claimed
JP-2007528986-A 2007-10-18 JP claimed
CN-100339405-C Liquid-absorbing sheet and nonaqueous electrolyte battery case SONY CHEMICALS (JP) 2007-09-26 CN claimed
EP-1636586-A2 ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES VENTANA MEDICAL SYSTEMS, INC. (US) 2006-03-22 EP claimed
CN-1751073-A Liquid absorbing sheet and non-aqueous electrolyte battery pack SONY CHEMICALS (JP) 2006-03-22 CN claimed
US-20050100976-A1 Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest VENTANA MEDICAL SYSTEMS, INC. 2005-05-12 US claimed
WO-2005003777-A2 ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED IN SITU DETECTION OF IMMUNOHISTOCHEMICAL EPITOPES AND NUCLEIC ACID SEQUENCES VENTANA MEDICAL SYSTEMS, INC. (US) 2005-01-13 WO claimed
US-20040265922-A1 Enzyme-catalyzed metal deposition for the enhanced in situ detection of immunohistochemical epitopes and nucleic acid sequences VENTANA MEDICAL SYSTEMS, INC. 2004-12-30 US claimed