Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723419 | 0.82 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL13123271 | 0.72 | PDE3B (0.47) | ALDH1A1KDM4EHPGDXDHLMNA | |
| SCHEMBL16313328 | 0.68 | KDM4E (0.40) | KDM4EXDHSLC22A12MAOB | |
| SCHEMBL13139799 | 0.65 | XDH (0.46) | ALDH1A1KDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL13004322 | 0.65 | XDH (0.48) | ALDH1A1KDM4EXDHHTTRXFP1 | |
| SCHEMBL8866260 | 0.64 | KDM4E (1.00) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL16495236 | 0.64 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL11707664 | 0.63 | KDM4E (0.60) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL7397366 | 0.63 | MAOA (0.51) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL7264627 | 0.63 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820700-B2 | 2-phenylpyridine derivative | ASTELLAS PHARMA INC. (JP) | 2010-10-26 | — | — | US | disclosed |