Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | AIP | O00170 | 1/20 | 0.54 |
| ▸ | SGTA | O43765 | 1/20 | 0.54 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.54 |
| ▸ | STIP1 | P31948 | 1/20 | 0.54 |
| ▸ | PPP5C | P53041 | 1/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.54 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.54 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.54 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.54 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180597 | 0.83 | L3MBTL1 (0.66) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL31060214 | 0.79 | MAPK8 (1.00) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL13126363 | 0.79 | MAPK8 (1.00) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL7676531 | 0.79 | MAPK8 (0.63) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL13781600 | 0.78 | HCAR2 (0.56) | MAPK8MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18177310 | 0.77 | MAPT (0.61) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL6999034 | 0.72 | MAPK8 (0.68) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL7670751 | 0.71 | MAPK8 (0.67) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL7886663 | 0.71 | MAPK8 (0.55) | MAPK8MAPTALDH1A1AIPSGTA | |
| SCHEMBL20852895 | 0.71 | ADORA1 (0.55) | MAPK8MAPTALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240720-A1 | ALLOSTERIC JNK INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240720-A1 | ALLOSTERIC JNK INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-09-23 | — | — | US | disclosed |
| WO-2010108115-A1 | ALLOSTERIC JNK INHIBITORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240720-A1 | ALLOSTERIC JNK INHIBITORS | MCL1, MAPKAPK2, MAP3K6 | MAPK8 21/4885MAPT 588/4885ALDH1A1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.