Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | AIP | O00170 | 1/20 | 0.50 |
| ▸ | SGTA | O43765 | 1/20 | 0.50 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.50 |
| ▸ | STIP1 | P31948 | 1/20 | 0.50 |
| ▸ | PPP5C | P53041 | 1/20 | 0.50 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.50 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.50 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.50 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13126363 | 0.80 | MAPK8 (1.00) | MAPK8ALDH1A1MAPTLMNAHTT | |
| SCHEMBL31060214 | 0.80 | MAPK8 (1.00) | MAPK8ALDH1A1MAPTLMNAHTT | |
| SCHEMBL6999034 | 0.77 | MAPK8 (0.68) | MAPK8ALDH1A1MAPTLMNAHTT | |
| SCHEMBL7505133 | 0.72 | KDM4E (0.67) | PTPN5GLSALDH1A1MAPTLMNA | |
| SCHEMBL18180597 | 0.72 | L3MBTL1 (0.66) | MAPK8ALDH1A1MAPTLMNAHTT | |
| SCHEMBL588980 | 0.72 | ICMT (0.62) | PTPN5ALDH1A1MAPTLMNAGAA | |
| SCHEMBL30958421 | 0.72 | ICMT (0.62) | PTPN5ALDH1A1MAPTLMNAGAA | |
| SCHEMBL13126361 | 0.71 | MAPK8 (0.65) | MAPK8ALDH1A1MAPTLMNAHTT | |
| SCHEMBL6999036 | 0.71 | ICMT (0.45) | MAPK8ALDH1A1MAPTLMNAHTT | |
| Hydrochloric Acid SCHEMBL3155846 | 0.71 | ICMT (0.60) | PTPN5ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |