Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 1.00 |
| ▸ | AIP | O00170 | 1/20 | 0.54 |
| ▸ | SGTA | O43765 | 1/20 | 0.54 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.54 |
| ▸ | STIP1 | P31948 | 1/20 | 0.54 |
| ▸ | PPP5C | P53041 | 1/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.54 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.54 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.54 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.54 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13126363 | 1.00 | MAPK8 (1.00) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL6999034 | 0.81 | MAPK8 (0.68) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL7670751 | 0.80 | MAPK8 (0.67) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL13126361 | 0.79 | MAPK8 (0.65) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL7890866 | 0.76 | MAPK8 (1.00) | MAPK8ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18180597 | 0.75 | L3MBTL1 (0.66) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL3711793 | 0.72 | MAPK8 (0.74) | MAPK8MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3713959 | 0.71 | MAPK8 (0.77) | MAPK8MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7886663 | 0.71 | MAPK8 (0.55) | MAPK8AIPSGTATOMM70STIP1 | |
| SCHEMBL13451636 | 0.71 | KMT2A (0.63) | MAPK8ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |