Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130682 | 0.90 | SMN1; SMN2 (0.43) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL13167840 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL17190983 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL17190976 | 0.77 | L3MBTL1 (0.59) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL7100469 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL16489784 | 0.74 | L3MBTL1 (0.60) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL16489779 | 0.74 | L3MBTL1 (0.60) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL12911265 | 0.74 | L3MBTL1 (0.60) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL12609515 | 0.74 | LMNA (0.68) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL5189232 | 0.74 | LMNA (0.68) | ALDH1A1LMNAL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563732-B2 | Oxyimino compounds and the use thereof | SHIONOGI & CO., LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20100240703-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240703-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | CACNA1A, CACNA1S, OPRM1 | ALDH1A1 886/4885LMNA 2216/4885L3MBTL1 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.