Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12082215 | 0.79 | APAF1 (0.42) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL15868611 | 0.78 | MAPT (0.44) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL3056333 | 0.74 | GABBR2 (0.47) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL3756089 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ESR1CYP3A4ESR2NAALAD2 | |
| SCHEMBL6294907 | 0.73 | LMNA (0.41) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL3380559 | 0.72 | MAPT (0.36) | MAPTGABBR2GABBR1POLBALDH1A1 | |
| SCHEMBL214563 | 0.72 | LMNA (0.47) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL28053820 | 0.72 | LMNA (0.40) | MAPTGABBR2GABBR1LMNAPOLB | |
| SCHEMBL1616269 | 0.71 | MAPT (0.44) | MAPTLMNAPOLBALDH1A1TSHR | |
| SCHEMBL15957862 | 0.71 | HDAC8 (0.44) | MAPTALDH1A1ESR1ESR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222497-A1 | BINDERS FOR PIGMENTED INK FORMULATIONS | DOUMAUX HOWARD A | 2010-09-02 | — | — | US | disclosed |