Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953807 | 0.89 | CYP1A2 (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL2953812 | 0.89 | CYP1A2 (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL2953811 | 0.89 | CYP1A2 (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL19216892 | 0.84 | ITGB1 (0.43) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11773441 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11773446 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL24378377 | 0.81 | CYP1A2 (0.40) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL2223617 | 0.81 | MAPT (0.47) | SMN1; SMN2ALDH1A1ALOX15TRPA1CYP3A4 | |
| SCHEMBL12442318 | 0.81 | MAPT (0.47) | SMN1; SMN2ALDH1A1ALOX15TRPA1CYP3A4 | |
| SCHEMBL19924329 | 0.80 | CYP1A2 (0.45) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222549-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | NIH-DEITR | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222549-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | TST, SCLY, AP2S1 | SMN1; SMN2 4012/4885CYP1A2 634/4885CYP2C9 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.