Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152593 | 0.87 | LMNA (0.50) | DYRK1ACYP19A1LMNAHTR6ABCC2 | |
| SCHEMBL15792328 | 0.81 | ICMT (0.49) | CYP19A1CNR2CNR1HTR6ALDH1A1 | |
| SCHEMBL31504554 | 0.78 | PDK1 (0.45) | DYRK1ACYP19A1ABCC2SMN1; SMN2DNM1 | |
| SCHEMBL10095336 | 0.77 | SMN1; SMN2 (0.57) | CYP19A1SMN1; SMN2MAPT | |
| SCHEMBL13806313 | 0.76 | CNR2 (0.50) | CNR2CNR1ALDH1A1 | |
| SCHEMBL24144136 | 0.76 | CYP19A1 (0.44) | CYP19A1CNR2LMNACNR1HTR6 | |
| SCHEMBL13152683 | 0.73 | LMNA (0.41) | DYRK1ACYP19A1CNR2LMNACNR1 | |
| Iodide SCHEMBL27771052 | 0.72 | CNR2 (0.48) | CNR2LMNACNR1ABCC2SMN1; SMN2 | |
| SCHEMBL14136899 | 0.72 | IDO1 (0.67) | CNR2LMNACNR1IDO1 | |
| SCHEMBL29556827 | 0.72 | MAPT (0.51) | LMNASMN1; SMN2ALDH1A1DNM1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |