Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24144137 | 0.85 | NR1D1 (0.46) | CNR2CNR1HTR6NR1D1TBXA2R | |
| SCHEMBL24143488 | 0.82 | NR1D1 (0.44) | CNR2CNR1HTR6NR1D1TBXA2R | |
| SCHEMBL24144934 | 0.80 | NR1D1 (0.42) | CNR2CNR1HTR6NR1D1TBXA2R | |
| SCHEMBL24144535 | 0.78 | NR1D1 (0.66) | CNR2CNR1NR1D1ICMT | |
| SCHEMBL13152564 | 0.76 | DYRK1A (0.43) | CYP19A1CNR2CNR1HTR6SMN1; SMN2 | |
| SCHEMBL22122330 | 0.75 | LMNA (0.45) | CYP19A1CNR2CNR1HTR6TBXAS1 | |
| SCHEMBL30592469 | 0.75 | CAMK2D (0.46) | CNR2CNR1NR1D1TBXA2RPTGER1 | |
| SCHEMBL26673710 | 0.75 | CAMK2D (0.46) | CNR2CNR1NR1D1TBXA2RPTGER1 | |
| SCHEMBL18508715 | 0.74 | DNM2 (0.56) | CNR2CNR1ICMTLMNA | |
| SCHEMBL10095336 | 0.72 | SMN1; SMN2 (0.57) | CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263278-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-12-30 | — | — | WO | disclosed |