SCHEMBL1315344

SCHEMBL1315344

Cc1ccccc1C(=CCO[SiH3])c1ccccc1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 3/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
CHRM3 P20309 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
HPGD P15428 2/20 0.34
GPR52 Q9Y2T5 1/20 0.34
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318497 0.82 SLC6A1 (0.40) SLC6A1ERCC5FEN1CHRM3GPR52
SCHEMBL7917611 0.77 SLC6A1 (0.34) SLC6A1ERCC5FEN1CHRM3MAOA
SCHEMBL7923510 0.75 SLC6A1 (0.36) SLC6A1CHRM3
SCHEMBL7923183 0.75 ERCC5 (0.39) SLC6A1ERCC5FEN1CHRM3MAOA
SCHEMBL5724863 0.72 SLC6A1 (0.43) SLC6A1ERCC5FEN1CHRM3MAOA
SCHEMBL5724891 0.72 SLC6A1 (0.43) SLC6A1ERCC5FEN1CHRM3MAOA
SCHEMBL8733487 0.71 TSHR (0.45) ERCC5FEN1CHRM3MAOAMAOB
SCHEMBL14415792 0.70 MAOA (0.42) SLC6A1ERCC5FEN1CHRM3MAOA
SCHEMBL7925193 0.69 SLC6A1 (0.40) SLC6A1KMT2A
SCHEMBL7925198 0.69 SLC6A1 (0.40) SLC6A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163950-B2 Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-24 US disclosed
US-20110275849-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES BANNOU TADASHI 2011-11-10 US disclosed
US-8008521-B2 Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2011-08-30 US disclosed
US-20090082585-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES BANNOU TADASHI 2009-03-26 US disclosed
US-7459577-B2 Reacting a chlorosilane with grignard reagent SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US disclosed
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275849-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES MLX, HAX1, RPS4X SLC6A1 3986/4885ERCC5 4270/4885FEN1 1995/4885
US-20090082585-A1 PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES MLX, HAX1, RPS4X SLC6A1 3986/4885ERCC5 4270/4885FEN1 1995/4885
US-20050070730-A1 Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes MLX, HAX1, GRIA3 SLC6A1 4335/4885ERCC5 4551/4885FEN1 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.