Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154605 | 0.87 | CTRC (0.56) | CTRCTHRBCYP1A2CYP2C9MAPT | |
| SCHEMBL7812766 | 0.85 | CTRC (1.00) | CTRCMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7825919 | 0.83 | THRB (0.63) | CTRCTHRBMAPTMEN1KMT2A | |
| SCHEMBL7825916 | 0.83 | THRB (0.63) | CTRCTHRBMAPTMEN1KMT2A | |
| SCHEMBL13154600 | 0.75 | CTRC (0.55) | CTRCMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7422807 | 0.74 | PTPN7 (0.69) | CTRCMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL18286211 | 0.72 | PTPN7 (0.70) | CTRCMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL31742271 | 0.71 | ALOX15 (0.55) | CTRCTHRBMAPTMEN1KMT2A | |
| SCHEMBL25281838 | 0.71 | PTGDR2 (0.57) | CTRCKMT2APKML3MBTL1TDP1 | |
| SCHEMBL7713953 | 0.70 | ALOX15 (0.68) | CTRCMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803966-B2 | Cosmetic and pharmaceutical compositions comprising compounds that display retinoid like activities | JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) | 2010-09-28 | — | — | US | disclosed |
| US-7803966-B2 | Cosmetic and pharmaceutical compositions comprising compounds that display retinoid like activities | JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) | 2010-09-28 | — | — | US | disclosed |
| US-20090203654-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS | KENVUE HOLDINGS FRANCE (FR) | 2009-08-13 | — | — | US | disclosed |
| US-20090203654-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS | KENVUE HOLDINGS FRANCE (FR) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203654-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS | EGFR, HDGF, CXCL8 | CTRC 3410/4885THRB 609/4885CYP1A2 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.