Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12734915 | 0.83 | PYCR1 (0.62) | PYCR1KMT2ALMNAHRH3MAPT | |
| SCHEMBL31725230 | 0.80 | PYCR1 (0.59) | PYCR1KMT2ALMNAHRH3MAPT | |
| SCHEMBL2238302 | 0.80 | ALDH1A1 (0.69) | PYCR1KMT2ALMNAHRH3MAPT | |
| SCHEMBL540981 | 0.76 | HRH3 (0.71) | PYCR1KMT2ALMNAHRH3MAPT | |
| SCHEMBL23640623 | 0.76 | PYCR1 (0.63) | PYCR1KMT2ALMNAHRH3MAPT | |
| SCHEMBL3302105 | 0.74 | KMT2A (0.67) | PYCR1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL6859304 | 0.73 | KMT2A (1.00) | PYCR1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9818052 | 0.73 | KMT2A (0.73) | PYCR1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL70979 | 0.73 | PYCR1 (0.59) | PYCR1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL50646 | 0.72 | MAPT (0.68) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816539-B2 | Derivatives of benzimidazole and imidazo-pyridine and their use as medicaments | IPSEN PHARMA S.A.S. (FR) | 2010-10-19 | — | — | US | disclosed |