Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25137173 | 0.84 | HRH3 (0.56) | HRH3LMNAALDH1A1LSSMAPT | |
| SCHEMBL13157944 | 0.83 | PYCR1 (0.59) | PYCR1KMT2AHRH3LMNAALDH1A1 | |
| SCHEMBL2238302 | 0.83 | ALDH1A1 (0.69) | PYCR1KMT2AHRH3LMNAALDH1A1 | |
| SCHEMBL31725230 | 0.83 | PYCR1 (0.59) | PYCR1KMT2AHRH3LMNAALDH1A1 | |
| SCHEMBL65825 | 0.83 | ALDH1A1 (0.59) | KMT2AHRH3ALDH1A1MEN1LSS | |
| SCHEMBL2913661 | 0.81 | HRH3 (0.52) | HRH3ALDH1A1LSSNOS3NOS1 | |
| SCHEMBL2771691 | 0.81 | HRH3 (0.52) | PYCR1HRH3ALDH1A1LSSMAPT | |
| Hydrochloric Acid SCHEMBL5065552 | 0.81 | ALDH1A1 (0.57) | KMT2AHRH3ALDH1A1MEN1LSS | |
| SCHEMBL7159528 | 0.81 | ALDH1A1 (0.57) | KMT2AHRH3ALDH1A1MEN1LSS | |
| Hydrochloric Acid SCHEMBL9834919 | 0.79 | HRH3 (0.50) | PYCR1KMT2AHRH3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-13 | — | — | US | disclosed |
| WO-2024160276-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-07 | — | — | US | disclosed |
| EP-1921077-B1 | AGENT FOR TREATING AND/OR PREVENTING SLEEP DISORDER | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-07-26 | — | — | EP | disclosed |
| US-9421532-B2 | Mononuclear iron complex and organic synthesis reaction using same | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-08-23 | — | — | US | disclosed |
| EP-3002283-A1 | THIAZOLE DERIVATIVES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-04-06 | — | — | EP | disclosed |
| US-20160023196-A1 | MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| US-8889718-B2 | Thiazole derivatives | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-20130267509-A1 | THIAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-10-10 | — | — | US | disclosed |
| US-7718808-B2 | Thiazole derivatives | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-05-18 | — | — | US | disclosed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| US-7316892-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) | 2008-01-08 | — | — | US | disclosed |
| US-7316892-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) | 2008-01-08 | — | — | US | disclosed |
| US-20070166647-A1 | Light sensitive planographic printing plate material and planographic printing plate manufacturing process | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070166647-A1 | Light sensitive planographic printing plate material and planographic printing plate manufacturing process | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070105919-A1 | adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20070105919-A1 | adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7192690-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7192690-B2 | Process of preparing planographic printing plate | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267509-A1 | THIAZOLE DERIVATIVES | THRA, CHD8, CYP2C8 | PYCR1 454/4885KMT2A 992/4885HRH3 658/4885 |
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | SMYD3, SMYD2, EHMT1 | PYCR1 1860/4885KMT2A 29/4885HRH3 715/4885 |
| US-20160023196-A1 | MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME | HNRNPL, ACSL3, RBCK1 | PYCR1 402/4885KMT2A 1735/4885HRH3 543/4885 |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | DGKG, DGKA, DGKK | PYCR1 3406/4885KMT2A 2375/4885HRH3 1257/4885 |
| US-20070105919-A1 | adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders | ADORA2A, ADORA3, ADORA1 | PYCR1 2418/4885KMT2A 3885/4885HRH3 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.