SCHEMBL13159232

SCHEMBL13159232

CC(C)(C)[Si](C)(C)Oc1ccc(CCCCO)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.48
CYP4A11 Q02928 2/20 0.44
CYP4F2 P78329 1/20 0.44
LTA4H P09960 1/20 0.41
EPHX2 P34913 1/20 0.41
PREP P48147 3/20 0.40
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
CA2 P00918 2/20 0.39
CALM1 P0DP23 1/20 0.38
IGF1R P08069 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25496223 0.98 PPARA (0.47) PPARACYP4A11CYP4F2LTA4HEPHX2
SCHEMBL2675281 0.95 PPARA (0.53) PPARACYP4A11CYP4F2LTA4HEPHX2
SCHEMBL2882151 0.88 PPARA (0.50) PPARACYP4A11CYP4F2PREPCA2
SCHEMBL18654007 0.84 PREP (0.40) PPARAPREPALDH1A1CALM1IGF1R
SCHEMBL9142598 0.84 PPARA (0.43) PPARACYP4A11CYP4F2LTA4HEPHX2
SCHEMBL9322867 0.83 CA12 (0.44) PPARACYP4A11CYP4F2LMNACYP3A4
SCHEMBL4521924 0.83 PREP (0.42) PPARAPREPMEN1ALDH1A1KMT2A
SCHEMBL1171890 0.83 PREP (0.40) PPARAPREPCALM1IGF1RALOX15
SCHEMBL18653924 0.82 PREP (0.41) PPARAPREPALDH1A1CALM1IGF1R
SCHEMBL318210 0.81 PPARA (0.47) PPARALTA4HPREPCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348362-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-11-02 US disclosed
US-9649373-B2 Neoseptins: small molecule adjuvants THE SCRIPPS INSTITUTE (US) 2017-05-16 US disclosed
EP-2958889-B1 NEOSEPTINS: SMALL MOLECULE ADJUVANTS SCRIPPS RESEARCH INST (US) 2017-03-22 EP disclosed
US-9102622-B2 Fatty acid amide hydrolase inhibitors UNIVERSITY OF CONNECTICUT (US) 2015-08-11 US disclosed
US-20100234379-A1 Dual modulation of endocannabinoid transport and fatty-acid amide hydrolase for treatment of excitotoxicity CONNECTICUT, UNIVERSITY OF 2010-09-16 US disclosed
US-20090306016-A1 FATTY ACID AMIDE HYDROLASE INHIBITORS UNIVERSITY OF CONNECTICUT 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306016-A1 FATTY ACID AMIDE HYDROLASE INHIBITORS FAAH, FAAH2, CNR2 PPARA 254/4885CYP4A11 559/4885CYP4F2 722/4885
US-20100234379-A1 Dual modulation of endocannabinoid transport and fatty-acid amide hydrolase for treatment of excitotoxicity FAAH, FAAH2, CNR2 PPARA 613/4885CYP4A11 3183/4885CYP4F2 3127/4885
US-20230348362-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT PPARA 798/4885CYP4A11 2691/4885CYP4F2 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.