Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675281 | 0.90 | PPARA (0.53) | PPARAPREPCA2CA12CA1 | |
| SCHEMBL13159232 | 0.88 | PPARA (0.48) | PPARAPREPCA2CA12CA1 | |
| SCHEMBL25496223 | 0.87 | PPARA (0.47) | PPARAPREPCA2CA12CA1 | |
| SCHEMBL318210 | 0.85 | PPARA (0.47) | PPARAPREPCA12CA1CA9 | |
| SCHEMBL3843622 | 0.84 | PREP (0.44) | PPARAPREPCA12CA1CA9 | |
| SCHEMBL2450429 | 0.82 | TAAR1 (0.53) | PREP | |
| SCHEMBL17661806 | 0.81 | PREP (0.43) | PPARAPREPCA12CA1CA9 | |
| SCHEMBL4521924 | 0.81 | PREP (0.42) | PPARAPREPCA12CA1CA9 | |
| SCHEMBL2997961 | 0.81 | PREP (0.42) | PPARAPREPCA12CA1CA9 | |
| SCHEMBL26781085 | 0.81 | PREP (0.49) | PREPCA12CA1CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365873-A1 | NITROGEN-FREE HYDROGEN SULPHIDE AND MERCAPTANS SCAVENGERS | TOTALENERGIES ONETECH (FR) | 2023-11-16 | — | — | US | disclosed |
| US-20230365873-A1 | NITROGEN-FREE HYDROGEN SULPHIDE AND MERCAPTANS SCAVENGERS | TOTALENERGIES ONETECH (FR) | 2023-11-16 | — | — | US | disclosed |
| EP-3774789-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195201-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-8314087-B2 | Nitrogen-containing heterocyclyl ketones and methods of use | AMGEN INC. (US) | 2012-11-20 | — | — | US | disclosed |
| US-8314087-B2 | Nitrogen-containing heterocyclyl ketones and methods of use | AMGEN INC. (US) | 2012-11-20 | — | — | US | disclosed |
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2114898-A2 | NITROGEN-CONTAINING HETEROCYCLYL KETONES AND THEIR USE AS C-MET INHIBITORS | Amgen Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | CHEN JAMES M | 2009-05-21 | — | — | US | disclosed |
| US-20080280917-A1 | Nitrogen-Containing heterocyclyl ketones and methods of use | AMGEN INC. (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1497261-B1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2007-12-19 | — | — | EP | disclosed |
| US-7271197-B2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 2007-09-18 | — | — | US | disclosed |
| US-20050256201-A1 | Phenethanolamine derivatives | GLAXO GROUP LIMITED | 2005-11-17 | — | — | US | disclosed |
| EP-1497261-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003091204-A1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-11-06 | — | — | WO | disclosed |
| US-4994476-A | Hypotensive agents | BRISTOL-MYERS COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0201558-A4 | DIHYDROPYRIDIN-3,5-DICARBOXYLATES INCORPORATING ARYLOXYPROPANOLAMINE MOIETIES. | BRISTOL MYERS CO (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0201558-A1 | DIHYDROPYRIDIN-3,5-DICARBOXYLATES INCORPORATING ARYLOXYPROPANOLAMINE MOIETIES | Bristol-Myers Squibb Company (US) | 1986-11-20 | — | — | EP | disclosed |
| WO-1986002640-A1 | DIHYDROPYRIDIN-3,5-DICARBOXYLATES INCORPORATING ARYLOXYPROPANOLAMINE MOIETIES | BRISTOL-MYERS COMPANY (US) | 1986-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365873-A1 | NITROGEN-FREE HYDROGEN SULPHIDE AND MERCAPTANS SCAVENGERS | SIGMAR1, GRHPR, CBR1 | PPARA 1717/4885PREP 2498/4885CA2 1177/4885 |
| US-20080280917-A1 | Nitrogen-Containing heterocyclyl ketones and methods of use | HGF, HGFAC, MET | PPARA 554/4885PREP 568/4885CA2 3315/4885 |
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | PPARA 1244/4885PREP 2250/4885CA2 4358/4885 |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | PHOSPHO1, G6PC1, PC | PPARA 234/4885PREP 1256/4885CA2 2638/4885 |
| US-20050256201-A1 | Phenethanolamine derivatives | PNMT, PHOSPHO1, NAPEPLD | PPARA 487/4885PREP 222/4885CA2 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.