Water

Water

SCHEMBL1316262

O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.[Zn].[Zn].[Zn].[Zn].[Zn]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GSK3B known ✓ P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL19510 1.00
Water SCHEMBL4951723 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL8061074 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL9245894 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL10408299 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL17102395 1.00
Water SCHEMBL8056743 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL16278601 1.00 GSK3B (0.50) GSK3B
Water SCHEMBL21048995 1.00
Water SCHEMBL12486397 1.00 GSK3B (0.50) GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114395178-A Basalt fiber-containing rubber compound and preparation method thereof 无锡市中惠橡胶科技有限公司 2022-04-26 CN claimed
CN-106753096-A A kind of building board binding agent 韦翔宇 2017-05-31 CN claimed
CN-106700172-A Ceramic-rubber composite sealing element material for hydraulic cylinder 安徽京鸿密封件技术有限公司 2017-05-24 CN claimed
CN-103000254-B A kind of solar cell back aluminum slurry with wide sintering process window JIANGSU RUIDE NEW ENERGY TECHNOLOGY CO., LTD. (CN) 2015-11-11 CN claimed
CN-103006907-B Traditional Chinese medicine composition for treating bone trauma and preparation method thereof XI AN CHIHO PHARMACEUTICAL CO LTD 2015-05-13 CN claimed
CN-103006907-A Traditional Chinese medicine composition for treating bone trauma and preparation method thereof XI AN CHIHO PHARMACEUTICAL CO LTD 2013-04-03 CN claimed
CN-103000254-A Solar cell aluminum-backed slurry with wide sintering process window JIANGSU RUIDE NEW ENERGY TECH 2013-03-27 CN claimed
CN-1793247-A Low-surface-energy fluorocarbon antifouling paint ZHENBANG FLUORINE COATING CO L (CN) 2006-06-28 CN claimed
CN-109833214-A A kind of mild oil-in-water type pickering sunlight screening skin-protecting product and preparation method thereof 广州澳希亚实业有限公司 2019-06-04 CN disclosed
CN-108766662-A The production method of the low warpage rear surface of solar cell aluminium paste of high efficiency 海宁市丁桥镇永畅知识产权服务部 2018-11-06 CN disclosed
CN-106753096-A A kind of building board binding agent 韦翔宇 2017-05-31 CN disclosed
CN-106700172-A Ceramic-rubber composite sealing element material for hydraulic cylinder 安徽京鸿密封件技术有限公司 2017-05-24 CN disclosed
CN-106432823-A Flame-retardant headband material 山西新华化工有限责任公司 2017-02-22 CN disclosed
CN-104418381-B A kind of method of extracting zinc oxide from blast furnace dedusting ash WANG QUANSHENG (CN) 2016-05-25 CN disclosed
CN-103000254-A Solar cell aluminum-backed slurry with wide sintering process window JIANGSU RUIDE NEW ENERGY TECH 2013-03-27 CN disclosed
US-20110272619-A1 PREPARATION FOR APPLICATION ONTO A CELLULOSIC FABRIC OR TEXTILE MATERIAL AND TEXTILE ARTICLES COMPRISING SAME STERLING PRODUCTS LIMITED (HK) 2011-11-10 US disclosed
CN-1822257-A Nano inductor and electronic ballast using nano inductor WEINA LIGHTING ENERGY SAVING N (CN) 2006-08-23 CN disclosed
CN-1793247-A Low-surface-energy fluorocarbon antifouling paint ZHENBANG FLUORINE COATING CO L (CN) 2006-06-28 CN disclosed
CN-1793247-A Low-surface-energy fluorocarbon antifouling paint ZHENBANG FLUORINE COATING CO L (CN) 2006-06-28 CN disclosed
WO-1987000051-A1 COMPOSITION FOR PREPARING A MEDICAMENT FOR TOPICAL TREATMENT OF PARADENTIUM DISEASES VOLI GIORGIO 1987-01-15 WO disclosed