SCHEMBL1316558

SCHEMBL1316558

COc1cccc(-c2ccc(C(=O)O)c(NC(=O)c3cc(N4CCOCC4)ccc3O)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
DHODH Q02127 3/20 0.48
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 2/20 0.46
LMNA P02545 2/20 0.45
HCRTR1 O43613 1/20 0.45
USP2 O75604 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
NTRK1 P04629 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318683 0.93 TSHR (0.46) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL1317541 0.92 PRSS12 (0.46) MEN1KMT2AALDH1A1POLBHCRTR1
SCHEMBL1317606 0.91 DHODH (0.48) MEN1KMT2ADHODHALDH1A1SMN1; SMN2
SCHEMBL1315851 0.89 HDAC1 (0.51) CYP1A2CYP3A4CYP2D6MAPTNTRK1
SCHEMBL1315061 0.88 MCL1 (0.46) MEN1KMT2AALDH1A1LMNACYP1A2
Hydrochloric Acid SCHEMBL1318051 0.88 HDAC1 (0.50) CYP1A2CYP3A4CYP2D6MAPTNTRK1
SCHEMBL1316102 0.87 MAPT (0.51) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL1315440 0.86 PRKDC (0.43) MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL1318044 0.85 MCL1 (0.49) DHODHUSP2CYP1A2CYP3A4CYP2D6
SCHEMBL1315586 0.85 MEN1 (0.52) MEN1KMT2AALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102333757-B N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2014-11-26 CN disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 MEN1 3020/4885KMT2A 950/4885DHODH 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.