Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26350478 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL3157252 | 0.81 | MEN1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7112182 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL19966969 | 0.78 | — | — | |
| SCHEMBL19286534 | 0.76 | — | — | |
| SCHEMBL7282809 | 0.73 | MEN1 (0.31) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5932747 | 0.73 | MEN1 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL17708254 | 0.73 | — | — | |
| SCHEMBL7367901 | 0.72 | MEN1 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL24515158 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459308-B2 | Broad spectrum inhibitors of filoviruses | MICROBIOTIX, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| CN-107250094-B | For extracting C from aqueous streams1To C4Quaternary phosphinate salts of carboxylic acids and co-solvents | 伊士曼化工公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-107257784-B | For extracting C from aqueous streams1To C4Quaternary carboxylate compositions of carboxylic acids | 伊士曼化工公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-107406469-B | For extracting C from aqueous streams1To C4Quaternary arylcarboxylate salt compositions of carboxylic acids | 伊士曼化工公司 | 2021-04-30 | — | — | CN | disclosed |
| US-20190292165-A1 | BROAD SPECTRUM INHIBITORS OF FILOVIRUSES | MICROBIOTIX, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| EP-3233872-A1 | QUATERNARY CARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS | Eastman Chemical Company (US) | 2017-10-25 | — | — | EP | disclosed |
| US-9611209-B1 | Quaternary arylcarboxylate compositions for extracting C1 to C4 carboxylic acids from aqueous streams | EASTMAN CHEMICAL COMPANY (US) | 2017-04-04 | — | — | US | disclosed |
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| WO-2016100768-A1 | QUATERNARY CARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS | EASTMAN CHEMICAL COMPANY (US) | 2016-06-23 | — | — | WO | disclosed |
| US-20160175737-A1 | Quaternary Carboxylate Compositions for Extracting C1 to C4 Carboxylic Acids from Aqueous Streams | EASTMAN CHEMICAL COMPANY (US) | 2016-06-23 | — | — | US | disclosed |
| US-8470850-B2 | Inhibitors of VEGF receptor and HGF receptor signalling | METHYLGENE INC. (CA) | 2013-06-25 | — | — | US | disclosed |
| US-20100249145-A1 | Inhibitors of VEGF Receptor and HGF Receptor Signaling | METHYLGENE, INC. | 2010-09-30 | — | — | US | disclosed |
| US-20100249145-A1 | Inhibitors of VEGF Receptor and HGF Receptor Signaling | METHYLGENE, INC. | 2010-09-30 | — | — | US | disclosed |
| US-7790729-B2 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC. (CA) | 2010-09-07 | — | — | US | disclosed |
| US-7790729-B2 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE INC. (CA) | 2010-09-07 | — | — | US | disclosed |
| US-20100216766-A1 | Inhibitors of VEGF Receptor and HGF Receptor Signalling | 92229129 QUEBEC INC. (CA) | 2010-08-26 | — | — | US | disclosed |
| US-7772247-B2 | Substituted thieno[3,2-d]pyridines as inhibitors of the VEGF receptor and HGF receptor | METHYLGENE INC. (CA) | 2010-08-10 | — | — | US | disclosed |
| US-7772247-B2 | Substituted thieno[3,2-d]pyridines as inhibitors of the VEGF receptor and HGF receptor | METHYLGENE INC. (CA) | 2010-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | MEN1 1184/4885KMT2A 1805/4885ALDH1A1 3922/4885 |
| US-20100249145-A1 | Inhibitors of VEGF Receptor and HGF Receptor Signaling | HGF, MET, FLT1 | MEN1 3655/4885KMT2A 3391/4885ALDH1A1 1649/4885 |
| US-11459308-B2 | Broad spectrum inhibitors of filoviruses | NPC1L1, NPC1, GBA1 | MEN1 3758/4885KMT2A 4257/4885ALDH1A1 3771/4885 |
| US-20100216766-A1 | Inhibitors of VEGF Receptor and HGF Receptor Signalling | HGF, MET, FLT1 | MEN1 3623/4885KMT2A 3438/4885ALDH1A1 1821/4885 |
| US-20190292165-A1 | BROAD SPECTRUM INHIBITORS OF FILOVIRUSES | NPC1L1, NPC1, GBA1 | MEN1 3758/4885KMT2A 4257/4885ALDH1A1 3771/4885 |
| US-20160175737-A1 | Quaternary Carboxylate Compositions for Extracting C1 to C4 Carboxylic Acids from Aqueous Streams | SLC16A3, CA4, SLC16A1 | MEN1 2014/4885KMT2A 3494/4885ALDH1A1 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.