Piperilate

Piperilate

SCHEMBL1316709

CCBr.O=C(OCCN1CCCCC1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
KMT2A Q03164 4/20 0.63
MEN1 O00255 3/20 0.63
GAA P10253 1/20 0.63
KDM4E B2RXH2 1/20 0.62
POLB P06746 1/20 0.54
CHRM2 P08172 4/20 0.54
CHRM1 P11229 4/20 0.54
CHRM3 P20309 3/20 0.54
CHRM4 P08173 2/20 0.54
CYP2D6 P10635 2/20 0.54
CHRM5 P08912 1/20 0.54
HTT P42858 1/20 0.53
LMNA P02545 1/20 0.48
HTR1A P08908 1/20 0.48
OPRM1 P35372 1/20 0.48
KCNH2 Q12809 1/20 0.48
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperilate SCHEMBL26493 0.94 ALDH1A1 (0.78) ALDH1A1KMT2AMEN1GAAKDM4E
Piperilate SCHEMBL1650954 0.92 ALDH1A1 (0.76) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL25142218 0.80 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL3361921 0.78 HTT (0.54) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL3365837 0.77 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL5158545 0.75 MEN1 (0.68) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL9588270 0.74 ALDH1A1 (0.68) ALDH1A1KMT2AMEN1GAAKDM4E
Hydrochloric Acid SCHEMBL9589541 0.73 ALDH1A1 (0.67) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL5161453 0.72 MEN1 (0.64) ALDH1A1KMT2AMEN1GAAKDM4E
Benactyzine SCHEMBL7799126 0.72 MEN1 (0.92) KMT2AMEN1KDM4EPOLBCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2647648-B1 Solid dosage form containing a low viscosity HYDROXYALKYL CELLULOSE NIPPON SODA CO (JP) 2017-08-09 EP disclosed
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
US-20150342895-A1 HYDROXYALKYL CELLULOSE NIPPON SODA CO (JP) 2015-12-03 US disclosed
EP-1953164-B1 THERAPEUTIC OR PROPHYLACTIC AGENT FOR FUNCTIONAL BOWEL DISORDER TORAY INDUSTRIES (JP) 2014-05-14 EP disclosed
EP-2647648-A1 HYDROXYALKYL CELLULOSE Nippon Soda Co., Ltd. (JP) 2013-10-09 EP disclosed
US-20130243870-A1 HYDROXYALKYL CELLULOSE NIPPON SODA CO., LTD. (JP) 2013-09-19 US disclosed
US-8058286-B2 Method for therapy of diarrhea-predominant irritable bowel disorders TORAY INDUSTRIES, INC. (JP) 2011-11-15 US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20090111843-A1 Therapeutic or Prophylactic Agent for Functional Bowel Disorder TORAY INDUSTRIES, INC. (JP) 2009-04-30 US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1953164-A1 THERAPEUTIC OR PROPHYLACTIC AGENT FOR FUNCTIONAL BOWEL DISORDER TORAY INDUSTRIES, INC. (JP) 2008-08-06 EP disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
US-20070166362-A1 Transdermal and transmucosal preparations KABUSHIKI KAISHA SANGI (JP) 2007-07-19 US disclosed
EP-1797900-A1 PREPARATION FOR PERCUTANEOUS/PERMUCOSAL ABSORPTION KABUSHIKI KAISHA SANGI (JP) 2007-06-20 EP disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111843-A1 Therapeutic or Prophylactic Agent for Functional Bowel Disorder SLC10A2, ALPI, SI ALDH1A1 2421/4885KMT2A 3808/4885MEN1 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.