Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709691 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL3527664 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10102461 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL19260738 | 0.90 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7838137 | 0.86 | KDM4E (0.61) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2927309 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL2920128 | 0.85 | KDM4E (0.60) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL6336768 | 0.83 | HTR4 (0.62) | ALDH1A1MEN1KMT2AACHEBCHE | |
| SCHEMBL13168044 | 0.83 | PKM (0.50) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL17375521 | 0.82 | SIRT6 (0.51) | ALDH1A1KDM4ELMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536184-B2 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-20100240893-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS AND PROCESS FOR MAKING NITROGENOUS HETEROCYCLIC COMPOUNDS AND INTERMEDIATES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-7709640-B2 | Nitrogenous heterocyclic compounds and process for making nitrogenous heterocyclic compounds and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240893-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS AND PROCESS FOR MAKING NITROGENOUS HETEROCYCLIC COMPOUNDS AND INTERMEDIATES THEREOF | NME1, NME2, TNNI3K | ALDH1A1 2813/4885KDM4E 1061/4885MEN1 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.