Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189398 | 0.93 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL6356064 | 0.78 | RAB9A (0.59) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL13927435 | 0.73 | MAP2K3 (0.52) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL9878243 | 0.72 | ALDH1A1 (0.83) | ALDH1A1CYP3A4CYP1A2MAPTHPGD | |
| SCHEMBL13189397 | 0.70 | MAP2K3 (0.49) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL13926376 | 0.70 | MAP2K3 (0.49) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL17263631 | 0.70 | MAP2K3 (0.49) | ALDH1A1CYP3A4CYP1A2RAB9AMAPT | |
| SCHEMBL13169787 | 0.69 | MAP2K3 (0.48) | ALDH1A1CYP3A4CYP1A2RAB9ANPC1 | |
| SCHEMBL13926842 | 0.69 | MAP2K3 (0.48) | ALDH1A1CYP3A4CYP1A2MAPTHPGD | |
| SCHEMBL13169762 | 0.69 | MAP2K3 (0.48) | ALDH1A1CYP3A4CYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9185909-B2 | Synthesis of resveratrol-based natural products | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-17 | — | — | US | disclosed |
| US-20100247462-A1 | SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS | NEW YORK, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247462-A1 | SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS | COASY, FDPS, RRP1B | ALDH1A1 4101/4885CYP3A4 1164/4885CYP1A2 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.