Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13927435 | 0.85 | MAP2K3 (0.52) | RAB9ANPC1HPGDTP53MAPT | |
| SCHEMBL13189398 | 0.85 | ALDH1A1 (0.51) | RAB9ANPC1HPGDTP53MAPT | |
| SCHEMBL6284499 | 0.79 | RAB9A (0.74) | RAB9ANPC1HPGDTP53MAPT | |
| SCHEMBL13169366 | 0.78 | ALDH1A1 (0.43) | RAB9ANPC1HPGDTP53MAPT | |
| Anisindione SCHEMBL29688105 | 0.75 | RAB9A (1.00) | RAB9ANPC1HPGDTP53MAPT | |
| Anisindione SCHEMBL49379 | 0.75 | RAB9A (1.00) | RAB9ANPC1HPGDTP53MAPT | |
| SCHEMBL13927208 | 0.73 | ALDH1A1 (0.44) | MAPTMAP2K3ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL30725970 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1HPGDMAPTALDH1A1 | |
| SCHEMBL10833433 | 0.71 | RAB9A (0.69) | RAB9ANPC1HPGDTP53MAPT | |
| SCHEMBL6324673 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903238-B2 | Substituted indenones as estrogenic agents | WYETH (US) | 2005-06-07 | — | — | US | disclosed |
| US-20030166643-A1 | Substituted indenones as estrogenic agents | WYETH | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166643-A1 | Substituted indenones as estrogenic agents | GPER1, ESR2, ESR1 | RAB9A 3245/4885NPC1 1845/4885HPGD 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.