Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894279 | 0.86 | FSCN1 (0.44) | FSCN1MAOBMAOACES2CES1 | |
| SCHEMBL1545185 | 0.80 | PKM (0.49) | FSCN1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1316220 | 0.80 | CYP1A2 (0.56) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL1316217 | 0.80 | CYP1A2 (0.56) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL3253845 | 0.78 | KMT2A (0.45) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL15047117 | 0.78 | CYP1A2 (0.43) | FSCN1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL13547957 | 0.76 | FSCN1 (0.44) | FSCN1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29669896 | 0.74 | CES2 (0.67) | MAOBMAOACES2CES1KIF11 | |
| SCHEMBL75801 | 0.74 | CES2 (0.67) | MAOBMAOACES2CES1KIF11 | |
| SCHEMBL8782702 | 0.74 | MAPT (0.46) | MAOBCES2CES1KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387557-B1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM SA (ES) | 2013-06-19 | — | — | EP | claimed |
| US-8163903-B2 | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM, S.A. (ES) | 2012-04-24 | — | — | US | claimed |
| EP-2387557-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | Interquim, S.A. (ES) | 2011-11-23 | — | — | EP | claimed |
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2011-11-10 | — | — | US | claimed |
| US-20110254078-A1 | METHOD FOR DEPOSITING SILICON NITRIDE FILM, COMPUTER-READABLE STORAGE MEDIUM, AND PLASMA CVD DEVICE | TOKYO ELECTRON LIMITED (JP) | 2011-10-20 | — | — | US | claimed |
| WO-2010081788-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2010-07-22 | — | — | WO | claimed |
| EP-2387557-B1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM SA (ES) | 2013-06-19 | — | — | EP | disclosed |
| US-8163903-B2 | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM, S.A. (ES) | 2012-04-24 | — | — | US | disclosed |
| US-8163903-B2 | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM, S.A. (ES) | 2012-04-24 | — | — | US | disclosed |
| US-8163903-B2 | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM, S.A. (ES) | 2012-04-24 | — | — | US | disclosed |
| CN-102282123-A | Process for the preparation of N- [5- (3-dimethylamino-acryloyl) -2-fluoro-phenyl ] -N-methyl-acetamide | — | 2011-12-14 | — | — | CN | disclosed |
| EP-2387557-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | Interquim, S.A. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2011-11-10 | — | — | US | disclosed |
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2011-11-10 | — | — | US | disclosed |
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2011-11-10 | — | — | US | disclosed |
| US-20110254078-A1 | METHOD FOR DEPOSITING SILICON NITRIDE FILM, COMPUTER-READABLE STORAGE MEDIUM, AND PLASMA CVD DEVICE | TOKYO ELECTRON LIMITED (JP) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081788-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081788-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | GABRA5, GABRA6, GABRD | FSCN1 4410/4885MAOB 763/4885MAOA 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.