Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261651 | 0.98 | KMT2A (0.64) | KMT2AGAAHTTCA2CA5A | |
| Dinitrophenylene SCHEMBL28343244 | 0.90 | KMT2A (0.57) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL29429379 | 0.89 | KMT2A (0.60) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL14575229 | 0.89 | KMT2A (0.60) | KMT2AGAAHTTCA2CA5A | |
| Phenol SCHEMBL28085209 | 0.87 | KMT2A (0.51) | KMT2AGAAHTTCA2CA5A | |
| Dinitrophenylene SCHEMBL27503833 | 0.85 | CYP1A2 (0.57) | KMT2AGAAHTTCA2CA5A | |
| Nitrobenzene SCHEMBL28829609 | 0.84 | LMNA (0.57) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL27799459 | 0.83 | KMT2A (0.62) | KMT2AGAAHTTCA2CA5A | |
| Dinitrophenylene SCHEMBL28111313 | 0.83 | CYP1A2 (0.54) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL8118078 | 0.83 | KMT2A (0.66) | KMT2AGAAHTTCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945272-A | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM SA | 2015-09-30 | — | — | CN | claimed |
| EP-2387557-B1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM SA (ES) | 2013-06-19 | — | — | EP | claimed |
| US-8163903-B2 | Process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide | INTERQUIM, S.A. (ES) | 2012-04-24 | — | — | US | claimed |
| CN-102282123-A | Process for the preparation of N- [5- (3-dimethylamino-acryloyl) -2-fluoro-phenyl ] -N-methyl-acetamide | — | 2011-12-14 | — | — | CN | claimed |
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | INTERQUIM, S.A. (ES) | 2011-11-10 | — | — | US | claimed |
| EP-4263646-B1 | STABILIZED EPOXY-ISOCYANATE MIXTURES AND OXAZOLIDINONE CONTAINING POLYMERS OBTAINED THEREFROM | BASF SE (DE) | 2025-02-12 | — | — | EP | disclosed |
| EP-4408533-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | Zevra Denmark A/S (DK) | 2024-08-07 | — | — | EP | disclosed |
| EP-4263646-A1 | STABILIZED EPOXY-ISOCYANATE MIXTURES AND OXAZOLIDINONE CONTAINING POLYMERS OBTAINED THEREFROM | BASF SE (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116601199-A | Stable epoxy-isocyanate mixtures and oxazolidinone-containing polymers therefrom | 巴斯夫欧洲公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2023053008-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | KEMPHARM DENMARK A/S (DK) | 2023-04-06 | — | — | WO | disclosed |
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| US-RE49361-E1 | Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-01-10 | — | — | US | disclosed |
| EP-0272563-B1 | TWO-STEP PROCESS FOR THE PRODUCTION OF MOULDED ARTICLES | BAYER AG (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0435060-A2 | Process for the preparation de plastic moulded pieces | BAYER AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| US-5021536-A | Curable mixtures of polyisocyanates, epoxides, alyklating agent to inhibit polymerization | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-4988549-A | CURABLE POLYISOCYANATE, POLYEPOXIDE REACTION MIXTURE ON POLYAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0357995-A2 | Multilayered article based ou polyamides | BAYER AG (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0331996-A1 | Storage-stable reaction resin mixture, preparation and use | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4788224-A | POLYISOCYANURATES, POLYOXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-29 | — | — | US | disclosed |
| EP-0272563-A2 | Two-step process for the production of moulded articles | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275809-A1 | PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE | GABRA5, GABRA6, GABRD | KMT2A 345/4885GAA 3560/4885HTT 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.