Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155541 | 0.93 | KMT2A (0.46) | KMT2AKDM4EALDH1A1KCNH2CXCR4 | |
| Hydrochloric Acid SCHEMBL2846173 | 0.92 | KMT2A (0.46) | KMT2AKDM4EALDH1A1KCNH2CXCR4 | |
| SCHEMBL13173102 | 0.89 | KCNH2 (0.53) | KMT2AALDH1A1KCNH2SIGMAR1DRD4 | |
| SCHEMBL2839038 | 0.86 | UBE2M (0.41) | KMT2AKDM4EALDH1A1KCNH2CXCR4 | |
| SCHEMBL13173146 | 0.85 | NPY5R (0.48) | — | |
| SCHEMBL13173108 | 0.84 | MCHR1 (0.46) | KMT2AKDM4EKCNH2LTA4H | |
| SCHEMBL13173169 | 0.84 | KCNH2 (0.50) | KCNH2SIGMAR1LTA4H | |
| SCHEMBL13173138 | 0.83 | CCR3 (0.48) | KDM4EKCNH2LTA4H | |
| SCHEMBL13173148 | 0.83 | ALDH1A1 (0.54) | KMT2AKDM4EALDH1A1SIGMAR1DRD4 | |
| SCHEMBL13173158 | 0.83 | KCNH2 (0.52) | KDM4EALDH1A1KCNH2SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139559-B2 | Nitrogen-containing six-membered aromatic ring derivatives and pharmaceutical products containing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140221409-A1 | NITROGEN-CONTAINING SIX-MEMBERED AROMATIC RING DERIVATIVES AND PHARMACEUTICAL PRODUCTS CONTAINING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120258978-A1 | NITROGEN-CONTAINING SIX-MEMBERED AROMATIC RING DERIVATIVES AND PHARMACEUTICAL PRODUCTS CONTAINING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258978-A1 | NITROGEN-CONTAINING SIX-MEMBERED AROMATIC RING DERIVATIVES AND PHARMACEUTICAL PRODUCTS CONTAINING THE SAME | NGF, VEGFA, BDNF | KMT2A 4167/4885KDM4E 3343/4885ALDH1A1 3305/4885 |
| US-20140221409-A1 | NITROGEN-CONTAINING SIX-MEMBERED AROMATIC RING DERIVATIVES AND PHARMACEUTICAL PRODUCTS CONTAINING THE SAME | NGF, VEGFA, NRP1 | KMT2A 4113/4885KDM4E 3752/4885ALDH1A1 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.