SCHEMBL131759

SCHEMBL131759

O=c1cc(-c2ccccc2O)oc2cc(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 1.00
KMT2A Q03164 7/20 1.00
HPGD P15428 6/20 1.00
TP53 P04637 4/20 1.00
ALOX15 P16050 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
AKR1C3 P42330 1/20 0.75
AKR1C2 P52895 1/20 0.75
AKR1C1 Q04828 1/20 0.75
CYP3A4 P08684 8/20 0.71
CYP2C9 P11712 6/20 0.71
CYP2C19 P33261 6/20 0.71
KDM4E B2RXH2 4/20 0.71
CYP19A1 P11511 2/20 0.68
MAOA P21397 2/20 0.68
MAOB P27338 2/20 0.68
CA12 O43570 1/20 0.68
AKR1B10 O60218 1/20 0.68
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373668 1.00 MEN1 (1.00) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL6832163 0.89 HPGD (0.80) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL30143812 0.88 HPGD (0.78) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL1058712 0.88 HPGD (0.78) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL312255 0.86 AKR1C3 (1.00) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL15676209 0.85 MEN1 (0.74) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL10810027 0.85 HPGD (0.74) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL7806215 0.84 KMT2A (0.72) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL4650047 0.83 HPGD (1.00) MEN1KMT2AHPGDTP53ALOX15
SCHEMBL7127255 0.82 KDM4E (0.73) MEN1KMT2AHPGDTP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282871-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF TIANJIN LIPOGEN TECH CO LTD (CN) 2025-09-11 US claimed
US-20250195452-A1 ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE IATERION, INC. 2025-06-19 US claimed
US-20240285755-A1 Adjuvants GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-08-29 US claimed
US-20240277751-A1 CRYSTALLINE POLYMORPHIC FORMS OF STING AGONISTS ASSOCIATED WITH METAL IONS CAPABLE OF MODULATING AN IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 US claimed
EP-4346894-A1 ADJUVANTS GlaxoSmithKline Biologicals S.A. (BE) 2024-04-10 EP claimed
EP-4342492-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF Tianjin Lipogen Technology Co., Ltd (CN) 2024-03-27 EP claimed
CN-117396222-A Pharmaceutical combination and use thereof 天津立博美华基因科技有限责任公司 2024-01-12 CN claimed
EP-4228657-A1 CRYSTALLINE POLYMORPHIC FORMS OF STING AGONISTS ASSOCIATED WITH METAL IONS CAPABLE OF MODULATING AN IMMUNE RESPONSE The Regents Of The University Of Michigan (US) 2023-08-23 EP claimed
CN-116390764-A Crystalline polymorphic forms of STING agonist bound to metal ions capable of modulating immune responses 密歇根大学董事会 2023-07-04 CN claimed
US-20220387470-A1 METHODS OF MODULATING IMMUNE ACTIVITY FLAGSHIP PIONEERING INNOVATIONS V, INC. 2022-12-08 US claimed
WO-2013006743-A2 PERSONAL CARE COMPOSITIONS WITH IMPROVED SOLUBILITY OF A SOLID COSMETIC ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2013-01-10 WO claimed
US-20130011347-A1 Personal Care Compositions With Improved Solubility of a Solid Cosmetic Active THE PROCTER & GAMBLE COMPANY 2013-01-10 US claimed
WO-2007084614-A2 HAIR GROWTH FORMULA SAKURA PROPERTIES, LLC (US) 2007-07-26 WO claimed
WO-2007084721-A2 SKIN PROTECTION AND MOISTURIZING COMPOSITIONS AND METHODS SAKURA PROPERTIES, LLC (US) 2007-07-26 WO claimed
US-20060210515-A1 HAIR GROWTH FORMULA SAKURA PROPERTIES, LLC 2006-09-21 US claimed
US-20060210524-A1 SKIN CARE COMPOSITION SAKURA PROPERTIES, LLC 2006-09-21 US claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130011347-A1 Personal Care Compositions With Improved Solubility of a Solid Cosmetic Active ASS1, C1R, CUTA MEN1 2813/4885KMT2A 3411/4885HPGD 1692/4885
US-20220387470-A1 METHODS OF MODULATING IMMUNE ACTIVITY STING1, IRF3, CGAS MEN1 4349/4885KMT2A 4415/4885HPGD 2044/4885
US-20250195452-A1 ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE ESR2, ESR1, ESRRB MEN1 2127/4885KMT2A 4051/4885HPGD 922/4885
US-20240285755-A1 Adjuvants STING1, TLR3, TLR9 MEN1 3362/4885KMT2A 2136/4885HPGD 3394/4885
US-20060210524-A1 SKIN CARE COMPOSITION CUTA, PLOD3, KRT18 MEN1 3918/4885KMT2A 1593/4885HPGD 2845/4885
US-20240277751-A1 CRYSTALLINE POLYMORPHIC FORMS OF STING AGONISTS ASSOCIATED WITH METAL IONS CAPABLE OF MODULATING AN IMMUNE RESPONSE STING1, CGAS, IRF3 MEN1 2384/4885KMT2A 4129/4885HPGD 2823/4885
US-20060210515-A1 HAIR GROWTH FORMULA HGF, HDGF, HGFAC MEN1 1159/4885KMT2A 3328/4885HPGD 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.