⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688069 | 0.84 | FOLH1 (0.34) | — | |
| SCHEMBL1688068 | 0.84 | PGD (0.33) | — | |
| SCHEMBL14679234 | 0.82 | TDP1 (0.33) | — | |
| SCHEMBL22872358 | 0.81 | CTSS (0.31) | — | |
| SCHEMBL13127084 | 0.81 | CTSS (0.31) | — | |
| SCHEMBL14306752 | 0.79 | MMP3 (0.31) | — | |
| SCHEMBL13676317 | 0.79 | MMP3 (0.31) | — | |
| SCHEMBL13166781 | 0.78 | — | — | |
| SCHEMBL27420074 | 0.78 | — | — | |
| SCHEMBL10079875 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100233190-A1 | TARGETED POLYMERIC PRODRUGS CONTAINING MULTIFUNCTIONAL LINKERS | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20090202573-A1 | POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES | ENZON PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |