Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306752 | 1.00 | MMP3 (0.31) | MMP3TGFBR1 | |
| SCHEMBL22872358 | 0.84 | CTSS (0.31) | — | |
| SCHEMBL13127084 | 0.84 | CTSS (0.31) | — | |
| SCHEMBL28099475 | 0.81 | MMP3 (0.30) | MMP3 | |
| SCHEMBL12301654 | 0.81 | FPR2 (0.35) | MMP3 | |
| SCHEMBL14374894 | 0.81 | GRN (0.33) | — | |
| SCHEMBL10079875 | 0.81 | — | — | |
| SCHEMBL12670717 | 0.81 | GRN (0.33) | — | |
| SCHEMBL14374242 | 0.79 | MMP3 (0.42) | MMP3 | |
| SCHEMBL13185094 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598232-B2 | Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-10-06 | — | — | US | disclosed |