Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187838 | 0.88 | RAB9A (0.53) | LMNAKMT2AMEN1CDC25ACDC25B | |
| SCHEMBL3716108 | 0.87 | LMNA (0.45) | LMNAHDAC6KMT2AMEN1CDC25A | |
| SCHEMBL13188800 | 0.87 | HDAC1 (0.55) | LMNAHDAC6SMPD1DEGS1HDAC1 | |
| SCHEMBL13188625 | 0.87 | HDAC6 (0.45) | HDAC6SMPD1KMT2ADEGS1HDAC1 | |
| SCHEMBL13188617 | 0.86 | HDAC6 (0.50) | HDAC6SMPD1DEGS1HDAC1KDM1A | |
| SCHEMBL13188500 | 0.85 | HDAC6 (0.44) | HDAC6SMPD1KMT2ADEGS1HDAC1 | |
| SCHEMBL13187833 | 0.85 | ADORA3 (0.53) | HDAC6SMPD1HDAC1NPC1RAB9A | |
| SCHEMBL13188875 | 0.84 | MKNK1 (0.55) | LMNAHDAC6SMPD1KMT2ADEGS1 | |
| SCHEMBL13187746 | 0.84 | DEGS1 (0.60) | LMNAHDAC6SMPD1KMT2ADEGS1 | |
| SCHEMBL13187914 | 0.82 | DEGS1 (0.50) | LMNAHDAC6SMPD1KMT2ADEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |