Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187836 | 0.85 | WNT1 (0.42) | SCN9AABL1BCRWNT1DYRK1A | |
| SCHEMBL3713958 | 0.85 | L3MBTL1 (0.42) | HPGDKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3709987 | 0.84 | POLB (0.45) | GAAHPGDKDM4EALDH1A1POLB | |
| SCHEMBL3713408 | 0.83 | L3MBTL1 (0.39) | DYRK1AHPGDALDH1A1POLBMAPT | |
| SCHEMBL3713386 | 0.82 | L3MBTL1 (0.46) | HPGDALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL3714672 | 0.82 | KMT2A (0.44) | GAAHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3715077 | 0.79 | AURKA (0.45) | GAASCN9AWNT1DYRK1AHPGD | |
| SCHEMBL3709357 | 0.79 | ACP1 (0.53) | KDM4EPTGS2SMN1; SMN2ACP1 | |
| SCHEMBL3714237 | 0.77 | KDM4E (0.43) | GAAHPGDKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3714572 | 0.77 | P2RY12 (0.46) | GAAWNT1DYRK1AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |