Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.40 |
| ▸ | ITGAL | P20701 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691770 | 0.79 | MC4R (0.47) | MAPTNLRP3SMN1; SMN2LMNAGAA | |
| SCHEMBL13188833 | 0.78 | DRD2 (0.46) | SMN1; SMN2LMNAGAAHTTUTS2R | |
| SCHEMBL13190971 | 0.72 | MC4R (0.48) | MAPTNLRP3CYP1A2MEN1CYP2C19 | |
| SCHEMBL13190967 | 0.72 | MAPT (0.47) | ALDH1A1MAPTNLRP3SMN1; SMN2LMNA | |
| SCHEMBL13691795 | 0.71 | DRD3 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28433860 | 0.69 | ALDH1A1 (0.52) | CYP3A4CYP2D6ALDH1A1ITGB2ICAM1 | |
| SCHEMBL13691792 | 0.69 | DRD2 (0.52) | MAPTNLRP3SMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL13190970 | 0.68 | DRD2 (0.51) | MAPTNLRP3SMN1; SMN2 | |
| SCHEMBL13689522 | 0.67 | DRD2 (0.49) | MAPTNLRP3SMN1; SMN2LMNAGAA | |
| SCHEMBL13691862 | 0.66 | UTS2R (0.43) | ALDH1A1MAPTNLRP3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |