Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321703 | 0.91 | NQO1 (0.50) | CALM1ESR1AHRPTGS2NQO1 | |
| SCHEMBL88823 | 0.89 | ALDH1A1 (0.61) | CALM1ALDH1A1PTGS2CYP19A1TSHR | |
| SCHEMBL13485083 | 0.89 | ALDH1A1 (0.61) | CALM1ESR1AHRALDH1A1NQO1 | |
| SCHEMBL13074291 | 0.89 | ALDH1A1 (0.61) | CALM1ESR1AHRALDH1A1NQO1 | |
| SCHEMBL12903697 | 0.85 | MAOB (0.47) | CALM1ALDH1A1PTGS2ABCB1 | |
| SCHEMBL11258820 | 0.84 | ALDH1A1 (0.53) | CALM1ALDH1A1PTGS2CYP19A1TSHR | |
| SCHEMBL8263328 | 0.83 | CALM1 (0.47) | CALM1ESR1AHRALDH1A1PTGS2 | |
| SCHEMBL8264227 | 0.83 | CALM1 (0.47) | CALM1ESR1AHRALDH1A1PTGS2 | |
| SCHEMBL13490528 | 0.83 | CALM1 (0.51) | CALM1ESR1AHRALDH1A1NQO1 | |
| SCHEMBL1911330 | 0.82 | ALDH1A1 (0.42) | CALM1AHRALDH1A1PTGS2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247462-A1 | SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS | NEW YORK, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247462-A1 | SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS | COASY, FDPS, RRP1B | CALM1 4087/4885ESR1 1577/4885AHR 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.