Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189262 | 0.91 | CALM1 (0.50) | NQO1TSHRPTGS2CALM1ESR1 | |
| SCHEMBL16951377 | 0.86 | NQO1 (0.42) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL1683212 | 0.86 | NQO1 (0.65) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL21432531 | 0.85 | L3MBTL1 (0.44) | NQO1LTA4HTSHRPTGS2CHRM2 | |
| SCHEMBL8048694 | 0.84 | LTA4H (0.48) | NQO1LTA4HPTGS2CALM1 | |
| SCHEMBL16951373 | 0.84 | NQO1 (0.41) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL13361876 | 0.84 | FGFR1 (0.41) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL16956809 | 0.84 | NQO1 (0.41) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL25468625 | 0.81 | NQO1 (0.38) | NQO1LTA4HTSHRTDP1TP53 | |
| SCHEMBL16956598 | 0.81 | ALDH1A1 (0.43) | NQO1LTA4HTP53MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008405-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |
| EP-3551625-A1 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018111904-A1 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2018-06-21 | — | — | WO | disclosed |
| US-9738753-B2 | Programmed degradation of polymers derived from biomass | NDSU RESEARCH FOUNDATION (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160108172-A1 | PROGRAMMED DEGRADATION OF POLYMERS DERIVED FROM BIOMASS | NORTH DAKOTA STATE UNIVERSITY | 2016-04-21 | — | — | US | disclosed |
| US-8133898-B2 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20100137310-A1 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108172-A1 | PROGRAMMED DEGRADATION OF POLYMERS DERIVED FROM BIOMASS | PARG, PPOX, PGLS | NQO1 333/4885LTA4H 1094/4885TSHR 4715/4885 |
| US-20100137310-A1 | RENIN INHIBITORS | REN, ACE, PRSS3 | NQO1 174/4885LTA4H 752/4885TSHR 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.