Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | AHR | P35869 | 2/20 | 0.59 |
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13074291 | 1.00 | ALDH1A1 (0.61) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL14461578 | 0.91 | ESR1 (0.52) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL10979139 | 0.89 | ESR1 (0.50) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL14832881 | 0.89 | CYP3A4 (0.53) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL9278662 | 0.89 | CALM1 (0.51) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL13189262 | 0.89 | CALM1 (0.50) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL12093390 | 0.89 | ESR1 (0.50) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL28106724 | 0.89 | ESR1 (0.50) | ALDH1A1ESR1AHRNQO1CALM1 | |
| SCHEMBL1683212 | 0.88 | NQO1 (0.65) | ALDH1A1ESR1AHRNQO1MAPT | |
| SCHEMBL8264227 | 0.85 | CALM1 (0.47) | ALDH1A1ESR1AHRNQO1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
| US-7666898-B2 | Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors | ILYPSA, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-20070135385-A1 | Methyl indoxam; obesity; dietectics; antidiabetic agents; insulin resistance; non-insulin dependent diabetes; glucose intolerance; hypercholesterolemia; hypertriglyceridemia; anticholesterol agents; metabolic disorders; foods;bioavailability; side effect reduction | ILYPSA, INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135385-A1 | Methyl indoxam; obesity; dietectics; antidiabetic agents; insulin resistance; non-insulin dependent diabetes; glucose intolerance; hypercholesterolemia; hypertriglyceridemia; anticholesterol agents; metabolic disorders; foods;bioavailability; side effect reduction | GPR119, INMT, PNLIP | ALDH1A1 2180/4885ESR1 4236/4885AHR 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.