Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | LDLR | P01130 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 6/20 | 0.38 |
| ▸ | NMT1 | P30419 | 6/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689393 | 0.78 | OPRM1 (0.42) | PLAU | |
| SCHEMBL13188849 | 0.77 | OPRM1 (0.42) | CTSLCTSSCTSKMETAP2METAP1 | |
| SCHEMBL13689529 | 0.77 | ITGB3 (0.37) | CTSLCTSSCTSKFURINGRIN1 | |
| SCHEMBL13188832 | 0.75 | OPRM1 (0.38) | — | |
| SCHEMBL13689532 | 0.75 | DRD4 (0.36) | FURIN | |
| SCHEMBL13691765 | 0.72 | NPC1 (0.44) | METAP2METAP1 | |
| SCHEMBL8512961 | 0.71 | MCHR1 (0.42) | METAP2METAP1 | |
| SCHEMBL13402577 | 0.70 | EPHX1 (0.46) | — | |
| SCHEMBL7549487 | 0.69 | NPY4R (0.46) | METAP2 | |
| SCHEMBL8515668 | 0.68 | HDAC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096853-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC1 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |