Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689532 | 0.98 | DRD4 (0.36) | ITGB3ITGA2BDRD4NPC1CASP1 | |
| SCHEMBL13691803 | 0.90 | ITGB3 (0.38) | ITGB3ITGA2BDRD4NPC1OPRM1 | |
| SCHEMBL13691796 | 0.88 | OPRM1 (0.38) | ITGB3ITGA2BDRD4NPC1OPRM1 | |
| SCHEMBL13689393 | 0.78 | OPRM1 (0.42) | NPC1OPRM1TMEM97SIGMAR1DRD2 | |
| SCHEMBL13689530 | 0.78 | OPRM1 (0.42) | NPC1OPRM1TMEM97SIGMAR1DRD2 | |
| SCHEMBL13188832 | 0.77 | OPRM1 (0.38) | DRD4NPC1OPRM1TMEM97SIGMAR1 | |
| SCHEMBL13190965 | 0.77 | CTSL (0.45) | FURINGRIN1GRIN2ACTSLCTSS | |
| SCHEMBL13691793 | 0.74 | NPC1 (0.47) | DRD4NPC1OPRM1TMEM97SIGMAR1 | |
| SCHEMBL13689525 | 0.73 | DRD3 (0.51) | DRD4NPC1DRD2DRD3 | |
| SCHEMBL13689520 | 0.73 | DRD3 (0.49) | DRD4NPC1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |