Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190968 | 0.86 | OPRM1 (0.46) | OPRM1TMEM97SIGMAR1OPRD1RAB9A | |
| SCHEMBL13188832 | 0.84 | OPRM1 (0.38) | OPRM1TMEM97SIGMAR1OPRD1RAB9A | |
| SCHEMBL13689532 | 0.79 | DRD4 (0.36) | OPRM1TMEM97SIGMAR1HDAC3HDAC1 | |
| SCHEMBL13190965 | 0.78 | CTSL (0.45) | PLAU | |
| SCHEMBL13689529 | 0.78 | ITGB3 (0.37) | OPRM1TMEM97SIGMAR1HDAC3HDAC1 | |
| SCHEMBL13188826 | 0.74 | OPRM1 (0.49) | OPRM1TMEM97SIGMAR1HDAC3HDAC1 | |
| SCHEMBL13689518 | 0.72 | OPRM1 (0.47) | OPRM1TMEM97SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8512961 | 0.72 | MCHR1 (0.42) | PDE4APDE4BPDE4CPDE4DPADI6 | |
| SCHEMBL13691793 | 0.72 | NPC1 (0.47) | OPRM1TMEM97SIGMAR1OPRD1RAB9A | |
| SCHEMBL13188835 | 0.72 | OPRM1 (0.44) | OPRM1TMEM97SIGMAR1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |