SCHEMBL1319720

SCHEMBL1319720

CC1=Cc2cccc(Br)c2C1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41
ALDH1A1 P00352 1/20 0.34
PIM1 P11309 1/20 0.32
CSNK1A1 P48729 1/20 0.32
CDK5 Q00535 1/20 0.32
ROCK1 Q13464 1/20 0.32
DYRK1A Q13627 1/20 0.32
LRRK2 Q5S007 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
DYRK1B Q9Y463 1/20 0.32
PARP10 Q53GL7 1/20 0.31
PARP11 Q9NR21 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31359427 1.00 TRPA1 (0.41) TRPA1ALDH1A1PIM1CSNK1A1CDK5
SCHEMBL5950996 0.78 TRPA1 (0.43) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL30667121 0.78 CYP2A6 (0.35) TRPA1ALDH1A1PARP10PARP11
SCHEMBL5953457 0.78 CYP2A6 (0.35) TRPA1ALDH1A1PARP10PARP11
SCHEMBL2960350 0.76 TRPA1 (0.42) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL1452615 0.75 ADRA2A (0.36) ALDH1A1
SCHEMBL2971904 0.75 TRPA1 (0.41) TRPA1PIM1CSNK1A1CDK5ROCK1
SCHEMBL2965960 0.75 PDE3B (0.31)
SCHEMBL12122310 0.75
SCHEMBL20125003 0.75 ACHE (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101707-A1 JULOLIDINE SUBSTITUTED METALLOCENE CATALYSTS ExxonMobil Technology and Engineering Company (US) 2026-05-15 WO disclosed
EP-4665774-A1 METALLOCENE CATALYST COMPOUNDS HAVING FERROCENYL SUBSTITUENTS ExxonMobil Technology and Engineering Company (US) 2025-12-24 EP disclosed
US-20250333549-A1 Process for Preparing a Catalyst for Olefin Polymerization HANWHA SOLUTIONS CORP (KR) 2025-10-30 US disclosed
EP-3875496-B1 METHOD FOR PREPARING CATALYST FOR OLEFIN POLYMERIZATION HANWHA SOLUTIONS CORP (KR) 2025-09-03 EP disclosed
US-12384860-B2 Hybrid supported metallocene catalyst and process for preparing polyethylene copolymer using the same LG CHEM, LTD. (KR) 2025-08-12 US disclosed
US-12384859-B2 Process for preparing a catalyst for olefin polymerization Hanwha Solutions Corporation (KR) 2025-08-12 US disclosed
EP-3398976-B1 HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING OLEFIN POLYMER BY USING SAME, AND OLEFIN POLYMER HAVING IMPROVED MELT STRENGTH HANWHA CHEMICAL CORP (KR) 2025-01-22 EP disclosed
US-12152101-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2024-11-26 US disclosed
US-20240343750-A1 Metallocene Catalyst Compounds for Producing Polyolefins EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-10-17 US disclosed
EP-4428166-A2 HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING OLEFIN POLYMER BY USING SAME, AND OLEFIN POLYMER HAVING IMPROVED MELT STRENGTH Hanwha Chemical Corporation (KR) 2024-09-11 EP disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
WO-2006065906-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX TRPA1 736/4885ALDH1A1 2587/4885PIM1 2877/4885
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization AP2M1, AP1M1, CPNE4 TRPA1 1845/4885ALDH1A1 1770/4885PIM1 1693/4885
US-20240343750-A1 Metallocene Catalyst Compounds for Producing Polyolefins MLX, TSNAX, TXLNA TRPA1 474/4885ALDH1A1 1232/4885PIM1 1191/4885
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 TRPA1 438/4885ALDH1A1 4332/4885PIM1 4466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.