Sugi Predict

Sugi Predict / Compounds / SCHEMBL13201212

SCHEMBL13201212

SCHEMBL13201212

C=C(C)C(=O)NC(=O)OCC1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.34
▸ ALDH1A1 P00352 5/20 0.33
▸ LMNA P02545 2/20 0.33
▸ POLB P06746 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ CTSL P07711 3/20 0.32
▸ EPHX2 P34913 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ PKM P14618 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1355052 0.81 ALDH1A1 (0.46) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL13201205 0.81 ALDH1A1 (0.35) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL13310502 0.80 KDM4E (0.38) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL13201194 0.79 ALDH1A1 (0.34) KDM4EALDH1A1EPHX2
SCHEMBL23550074 0.78 KDM4E (0.46) KDM4EALDH1A1LMNAPOLBALOX15
Methacrylic Acid SCHEMBL5066175 0.78 ALDH1A1 (0.43) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL13402554 0.78 CTSL (0.38) KDM4EPOLBALOX15CTSL
SCHEMBL13443362 0.78 KDM4E (0.40) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL13714698 0.78 KDM4E (0.40) KDM4EALDH1A1LMNAPOLBALOX15
SCHEMBL414809 0.78 EPHX2 (0.41) KDM4EALDH1A1LMNAPOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772341-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2010-08-10 — — US disclosed
US-7772341-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2010-08-10 — — US disclosed
US-7728090-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2010-06-01 — — US disclosed
US-7728090-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2010-06-01 — — US disclosed
US-20100087659-A1 NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES LIAW DER-JANG 2010-04-08 — — US disclosed
US-20100087659-A1 NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES LIAW DER-JANG 2010-04-08 — — US disclosed
US-7323518-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-01-29 — — US disclosed
US-7323518-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-01-29 — — US disclosed
US-7309751-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2007-12-18 — — US disclosed
US-7309751-B2 Norbornene compounds with cross-linkable groups and their derivatives NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2007-12-18 — — US disclosed
US-20070073018-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073018-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073079-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073079-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073080-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073080-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073017-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070073017-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-29 — — US disclosed
US-20070066774-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-22 — — US disclosed
US-20070066774-A1 Norbornene compounds with cross-linkable groups and their derivatives LIAW DER-JANG 2007-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070073080-A1 Norbornene compounds with cross-linkable groups and their derivatives OXER1, SQLE, ALOX12 KDM4E 3761/4885ALDH1A1 638/4885LMNA 1450/4885
US-20070073079-A1 Norbornene compounds with cross-linkable groups and their derivatives OXER1, SQLE, ALOX12 KDM4E 3761/4885ALDH1A1 638/4885LMNA 1450/4885
US-20100087659-A1 NORBORNENE COMPOUNDS WITH CROSS-LINKABLE GROUPS AND THEIR DERIVATIVES SQLE, OXER1, MACF1 KDM4E 3982/4885ALDH1A1 476/4885LMNA 1318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.