Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760565 | 0.88 | PSMD14 (0.57) | SLC40A1PSMD14HTR1AADRA1DADRA1A | |
| SCHEMBL14871760 | 0.77 | HTR1A (0.53) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8277995 | 0.77 | HTR1A (0.53) | SLC40A1PSMD14HTR1AADRA1DADRA1A | |
| SCHEMBL2963509 | 0.76 | PSMD14 (0.45) | PSMD14L3MBTL1NPC1MEN1HSP90AA1 | |
| SCHEMBL12042114 | 0.76 | SLC40A1 (0.49) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4364047 | 0.76 | KDM4E (0.49) | SLC40A1PSMD14HTR1AL3MBTL1MEN1 | |
| SCHEMBL6589147 | 0.76 | NR4A2 (0.56) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1714045 | 0.76 | KDM4E (0.54) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7247375 | 0.76 | NSD2 (0.54) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28304013 | 0.76 | SLC40A1 (0.49) | SLC40A1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767818-B2 | Hepatitis C inhibitor dipeptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-03 | — | — | US | disclosed |
| US-20090156822-A1 | Hepatitis C Inhibitor Dipeptide Analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
| US-7511157-B2 | racemic mixtures, stereoisomers or optical isomers, useful as protease inhibitors; viricides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156822-A1 | Hepatitis C Inhibitor Dipeptide Analogs | DPP3, CTSC, ANPEP | SLC40A1 1608/4885PSMD14 2840/4885HTR1A 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.